(TFE) Turbo field echo is a gradient echo pulse sequence with data acquisition after an initial 180° (similar to IR) preparation pulse for contrast enhancement. The difference between a FFE and TFE other than the speed of the sequence is that the image is acquired while approaching steady state (the echoes are collected during the time in which the tissues are experiencing T1 relaxation).
The contrast is prepared one time, which means the contrast is changing while the echoes are collected and can be manipulated by selecting the type and timing of the prepulse. A delay time is given before the actual image acquisition. To achieve T1 contrast the 180° prepulse is followed by an operator selected delay time, that results in no signal from the targeted tissue. So when the echoes are acquired, no signal is present, additional RF spoiling is performed to optimize for T1 contrast. The delay chosen corresponds to when T1 relaxation reaches and suppresses T1 signal or optimizes the difference between tissues. Contrast for these sequences are enhanced when K-space is filled using a centric or low-high ordering. A TFE can be acquired with a 2D or 3D technique and with or without T1, T2 weighting.
See Ultrafast Gradient Echo Sequence, TurboFLASH and Magnetization Prepared Rapid Gradient Echo (MPRAGE).

A gradient echo is generated by using a pair of bipolar gradient pulses. The gradient field is negatively pulsed, causing the spins of the xy-magnetization to dephase. A second gradient pulse is applied with the opposite polarity. During the pulsing, the spins that dephased begin to rephase and generate a gradient echo.
Spoiling can be accomplished by RF or a gradient. The incoherent RF spoiled type of a gradient echo sequence use a continuous shifting of the RF pulse to spoil the residual transverse magnetization. The phase of the RF excitation and receiver channel are varied pseudo randomly with each excitation cycle to prevent the xy magnetization from achieving steady state. T2* does not dominate image contrast, so T1 and PD weighting is practical. This method is effective and can be used to achieve a shorter TR, due to a lack of additional gradients. Spoiling eliminates the effect of the remaining xy-magnetization and leads to steady state longitudinal magnetization. These sequences can be used for breath hold, dynamic imaging and in cine and volume acquisitions.

Categories of negative oral contrast agents:
Negative oral contrast media are usually based on superparamagnetic particles and act by inducing local field inhomogeneities, which results in shortening of both T1 and T2 relaxation times. Superparamagnetic contrast agents have predominant T2 weighted effects. Biphasic contrast media are agents that have different signal intensities on different sequences, depending on the concentration at which they are used.
Suitable materials for oral contrast agents should have little or no absorption by the stomach or intestines, complete excretion, no motion or susceptibility artifacts, affordability, and uniform marking of the gastrointestinal tract. Benefits of negative oral contrast agents are the reduction of ghosting artifacts caused by the lack of signal. Superparamagnetic iron oxides produce also in low concentrations a noticeable signal loss; but can generate susceptibility artifacts especially in gradient echo sequences. Perfluorochemicals do not dilute in the bowel because they are not miscible with water.
High cost, poor availability, and limited evaluations of side effects are possible disadvantages.
Negative oral contrast agents are used e.g., in MRCP, where the ingestion of 600-900 ml of SPIO cancels out the signal intensity of the lumen (in addition after the injection of a gadolinium-based contrast medium, the enhancement of the inflammatory tissues is clearer seen), and in MR abdominal imaging of Crohn's disease in combination with mannitol.

Blueberry or pineapple juices are useable for examinations of the pancreas (MRCP, upper abdominal imaging) as cheep contrast agents, because of the content of magnetic substances (e.g. manganese).

See also Ferristene, Ferumoxsil, Oral Magnetic Particles, Gastrointestinal Imaging.

Contrast enhanced GRE sequences provide T2 contrast but have a relatively poor SNR. Repetitive RF pulses with small flip angles together with appropriate gradient profiles lead to the superposition of two resonance signals.
The first signal is due to the free induction decay FID observed after the first and all ensuing RF excitations.
The second is a resonance signal obtained as a result of a spin echo generated by the second and all addicted RF-pulses.
Hence it is absent after the first excitation, it is a result of the free induction decay of the second to last RF-excitation and has a TE, which is almost 2TR. For this echo to occur the gradients have to be completely symmetrical relative to the half time between two RF-pulses, a condition that makes it difficult to integrate this pulse sequence into a multiple slice imaging technique. The second signal not only contains echo contributions from free induction decay, but obviously weakened by T2-decay. Since the echo is generated by a RF-pulse, it is truly T2 rather than T2* weighted. Correspondingly it is also less sensitive to susceptibility changes and field inhomogeneities.
Companies use different acronyms to describe certain techniques.
Different terms (see also acronyms) for these gradient echo pulse sequences:
CE-FAST Contrast Enhanced Fourier Acquired Steady State,
CE-FFE Contrast Enhanced Fast Field Echo,
CE-GRE Contrast Enhanced Gradient-Echo,
DE-FGR Driven Equilibrium FGR,
FADE FASE Acquisition Double Echo,
PSIF Reverse Fast Imaging with Steady State Precession,
SSFP Steady State Free Precession,
T2 FFE Contrast Enhanced Fast Field Echo (T2 weighted).
In this context, 'contrast enhanced' refers to the pulse sequence, it does not mean enhancement with a contrast agent.

Contrast is the relative difference of signal intensities in two adjacent regions of an image.
Due to the T1 and T2 relaxation properties in magnetic resonance imaging, differentiation between various tissues in the body is possible. Tissue contrast is affected by not only the T1 and T2 values of specific tissues, but also the differences in the magnetic field strength, temperature changes, and many other factors. Good tissue contrast relies on optimal selection of appropriate pulse sequences (spin echo, inversion recovery, gradient echo, turbo sequences and slice profile).
Important pulse sequence parameters are TR (repetition time), TE (time to echo or echo time), TI (time for inversion or inversion time) and flip angle. They are associated with such parameters as proton density and T1 or T2 relaxation times. The values of these parameters are influenced differently by different tissues and by healthy and diseased sections of the same tissue.
For the T1 weighting it is important to select a correct TR or TI. T2 weighted images depend on a correct choice of the TE. Tissues vary in their T1 and T2 times, which are manipulated in MRI by selection of TR, TI, and TE, respectively. Flip angles mainly affect the strength of the signal measured, but also affect the TR/TI/TE parameters.
Conditions necessary to produce different weighted images:
T1 Weighted Image: TR value equal or less than the tissue specific T1 time - TE value less than the tissue specific T2 time.
T2 Weighted Image: TR value much greater than the tissue specific T1 time - TE value greater or equal than the tissue specific T2 time.
Proton Density Weighted Image: TR value much greater than the tissue specific T1 time - TE value less than the tissue specific T2 time.

See also Image Contrast Characteristics, Contrast Reversal, Contrast Resolution, and Contrast to Noise Ratio.