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DeviceForum -
related threadsInfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.
 
Magnetic resonance imaging (MRI) is based on the magnetic resonance phenomenon, and is used for medical diagnostic imaging since ca. 1977 (see also MRI History).
The first developed MRI devices were constructed as long narrow tunnels. In the meantime the magnets became shorter and wider. In addition to this short bore magnet design, open MRI machines were created. MRI machines with open design have commonly either horizontal or vertical opposite installed magnets and obtain more space and air around the patient during the MRI test.
The basic hardware components of all MRI systems are the magnet, producing a stable and very intense magnetic field, the gradient coils, creating a variable field and radio frequency (RF) coils which are used to transmit energy and to encode spatial positioning. A computer controls the MRI scanning operation and processes the information.
The range of used field strengths for medical imaging is from 0.15 to 3 T. The open MRI magnets have usually field strength in the range 0.2 Tesla to 0.35 Tesla. The higher field MRI devices are commonly solenoid with short bore superconducting magnets, which provide homogeneous fields of high stability.
There are this different types of magnets:
The majority of superconductive magnets are based on niobium-titanium (NbTi) alloys, which are very reliable and require extremely uniform fields and extreme stability over time, but require a liquid helium cryogenic system to keep the conductors at approximately 4.2 Kelvin (-268.8° Celsius). To maintain this temperature the magnet is enclosed and cooled by a cryogen containing liquid helium (sometimes also nitrogen).
The gradient coils are required to produce a linear variation in field along one direction, and to have high efficiency, low inductance and low resistance, in order to minimize the current requirements and heat deposition. A Maxwell coil usually produces linear variation in field along the z-axis; in the other two axes it is best done using a saddle coil, such as the Golay coil.
The radio frequency coils used to excite the nuclei fall into two main categories; surface coils and volume coils. The essential element for spatial encoding, the gradient coil sub-system of the MRI scanner is responsible for the encoding of specialized contrast such as flow information, diffusion information, and modulation of magnetization for spatial tagging.
An analog to digital converter turns the nuclear magnetic resonance signal to a digital signal. The digital signal is then sent to an image processor for Fourier transformation and the image of the MRI scan is displayed on a monitor.

For Ultrasound Imaging (USI) see Ultrasound Machine at Medical-Ultrasound-Imaging.com.

See also the related poll results: 'In 2010 your scanner will probably work with a field strength of' and 'Most outages of your scanning system are caused by failure of'
Radiology-tip.comradGamma Camera,  Linear Accelerator
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Medical-Ultrasound-Imaging.comUltrasound Machine,  Real-Time Scanner
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Further Reading:
  News & More:
small-steps-can-yield-big-energy-savings-and-cut-emissions-mris
Thursday, 27 April 2023   by www.itnonline.com    
Portable MRI can detect brain abnormalities at bedside
Tuesday, 8 September 2020   by news.yale.edu    
Point-of-Care MRI Secures FDA 510(k) Clearance
Thursday, 30 April 2020   by www.diagnosticimaging.com    
World's First Portable MRI Cleared by FDA
Monday, 17 February 2020   by www.medgadget.com    
Low Power MRI Helps Image Lungs, Brings Costs Down
Thursday, 10 October 2019   by www.medgadget.com    
Cheap, portable scanners could transform brain imaging. But how will scientists deliver the data?
Tuesday, 16 April 2019   by www.sciencemag.org    
The world's strongest MRI machines are pushing human imaging to new limits
Wednesday, 31 October 2018   by www.nature.com    
Kyoto University and Canon reduce cost of MRI scanner to one tenth
Monday, 11 January 2016   by www.electronicsweekly.com    
A transportable MRI machine to speed up the diagnosis and treatment of stroke patients
Wednesday, 22 April 2015   by medicalxpress.com    
Portable 'battlefield MRI' comes out of the lab
Thursday, 30 April 2015   by physicsworld.com    
Chemists develop MRI technique for peeking inside battery-like devices
Friday, 1 August 2014   by www.eurekalert.org    
New devices doubles down to detect and map brain signals
Monday, 23 July 2012   by scienceblog.com    
MRI Resources 
Stimulator pool - Directories - MR Guided Interventions - Guidance - Anatomy - MRI Centers
 
Hahn Echo
 
Production of spin echo by repeated RF pulses. First observed using equal (90°) RF pulses, now commonly used to describe refocusing of transverse magnetization by a 180° RF pulse. By choosing long echo delay times, the spins in a Hahn echo first dephase for a long time, then rephase, which makes the Hahn pulse sequence more susceptible to diffusion effects.
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Further Reading:
  Basics:
Magnetic resonance imaging
   by www.scholarpedia.org    
MRI Resources 
Implant and Prosthesis pool - Developers - Mobile MRI - MRI Technician and Technologist Jobs - Musculoskeletal and Joint MRI - Stimulator pool
 
NC100150 InjectionInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Short name: NC100150, PEG-feron, generic name: Feruglose, preliminary trade name: Clariscan™
NC100150 injection is the code name for an USPIO (ultrasmall superparamagnetic iron oxide) MRI contrast agent under development. Microvessel permeability depends on functional and morphologic characteristics of cancer vessels and on physicochemical properties of the injected contrast medium molecule.
USPIO particles have a favorable pharmacological and tolerance profile and are being tested clinically of the potential for the quantitative characterization of tumor microvasculature and specifically for measures of the microvessel permeability. Iron-based products take advantage of their large molecular size, which prevents diffusion into body tissues. These agents are disposed of by the liver and spleen as particulate matter.
NC100150 Injection (Nycomed Amersham, Amersham Health ) consists of USPIO particles that are composed of single crystals (4- to 7-nm diameter) and stabilized with a carbohydrate polyethylene glycol (PEG) coat. The iron oxide particles have to be suspended in an isotonic glucose solution. The final diameter of an USPIO particle is approximately 20 nm. Blood pool half-life is more than two hours in humans; the particles are taken up by the mononuclear phagocyte system and distributed mainly to the liver and spleen.
NC100150 would compete with the contrast agents Ferumoxytol from AMAG Pharmaceuticals, Inc. and Vasovist™ from EPIX Pharmaceuticals, Inc., but at this time the development of NC100150 Injection/Clariscan™ is discontinued.
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High Field MRI
 
The principal advantage of MRI at high field is the increase in signal to noise ratio. This can be used to improve anatomic and/or temporal resolution and reduce scan time while preserving image quality. MRI devices for whole body imaging for human use are available up to 3 tesla (3T). Functional MRI (fMRI) and MR spectroscopy (MRS) benefit significantly. In addition, 3T machines have a great utility in applications such as TOF MRA and DTI. Higher field strengths are used for imaging of small parts of the body or scientific animal experiments. Higher contrast may permit reduction of gadolinium doses and, in some cases, earlier detection of disease.
Using high field MRI//MRS, the RF-wavelength and the dimension of the human body complicating the development of MR coils. The absorption of RF power causes heating of the tissue. The energy deposited in the patient's tissues is fourfold higher at 3T than at 1.5T. The specific absorption rate (SAR) induced temperature changes of the human body are the most important safety issue of high field MRI//MRS.
Susceptibility and chemical shift dispersion increase like T1, therefore high field MRI occasionally exhibits imaging artifacts. Most are obvious and easily recognized but some are subtle and mimic diseases. A thorough understanding of these artifacts is important to avoid potential pitfalls. Some imaging techniques or procedures can be utilized to remove or identify artifacts.

See also Diffusion Tensor Imaging.

See also the related poll result: 'In 2010 your scanner will probably work with a field strength of'
Medical-Ultrasound-Imaging.comMagnetic Resonance Guided Focused Ultrasound,  High Intensity Focused Ultrasound
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Further Reading:
  Basics:
Next-generation 7 T scanner ramps the resolution of brain MR imaging
Wednesday, 17 January 2024   by physicsworld.com    
A paired dataset of T1- and T2-weighted MRI at 3 Tesla and 7 Tesla
Thursday, 27 July 2023   by www.nature.com    
CLINICAL WHOLE BODY MRI AT 3.0 T(.pdf)
2001
Musculoskeletal MRI at 3.0 T: Relaxation Times and Image Contrast
Sunday, 1 August 2004   by www.ajronline.org    
  News & More:
How safe is 7T MRI for patients with neurosurgical implants?
Thursday, 17 November 2022   by healthimaging.com    
Impact of Magnetic Field Inhomogeneity on the Quality of Magnetic Resonance Images and Compensation Techniques: A Review
Saturday, 1 October 2022   by www.dovepress.com    
7-T clinical MRI of the shoulder in patients with suspected lesions of the rotator cuff
Friday, 7 February 2020   by eurradiolexp.springeropen.com    
A 100-hour MRI scan captured the most detailed look yet at a whole human brain
Monday, 8 July 2019   by www.sciencenews.or    
T2-Weighted Liver MRI Using the MultiVane Technique at 3T: Comparison with Conventional T2-Weighted MRI
Friday, 16 October 2015   by www.ncbi.nlm.nih.gov    
Ultra-high-field MRI reveals language centres in the brain in much more detail
Tuesday, 28 October 2014   by medicalxpress.com    
Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T
Thursday, 20 June 2013   by www.plosone.org    
High-Resolution, Spin-Echo BOLD, and CBF fMRI at 4 and 7 T(.pdf)
October 2002   by otg.downstate.edu    
Vascular Filters of Functional MRI: Spatial Localization Using BOLD and CBV Contrast
MRI Resources 
Case Studies - Fluorescence - Crystallography - Shoulder MRI - Brain MRI - MRI Centers
 
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MRI is trending to low field magnets :
reduced costs will lead to this change 
AI will close the gap to high field 
only in remote areas 
is only temporary 
never 

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