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Spectroscopy
 
Edward Purcell and Felix Bloch discovered the basic of spectroscopy in 1946 (see MRI History). Nuclear magnetic resonance spectroscopy (NMR Spectroscopy or MRS) is an analytical tool, based on nuclei that have a spin (nuclei with an odd number of neutrons and/or protons) like 1H, 13C, 17O, 19F, 31P etc..
Through nuclear magnetic principles as precession, chemical shift, spin spin coupling etc., the analysis of the content, purity, and molecular structure of a sample is possible. The spectrum produced by this process contains a number of peaks; the highs and the positions of these peaks allow the exact analysis. Unknown compounds can be matched against spectral libraries. Even very complex organic compounds as enzymes and proteins can be determined. For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different techniques available.
See Spectroscopic Imaging Techniques.
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    • Radio Frequency Pulse
    • Chemical Shift Imaging
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Further Reading:
  Basics:
MR Spectroscopy May Help Avoid Invasive Procedures And Treatments For Recurrent Brain Lesions
Wednesday, 11 February 2009   by www.sciencedaily.com    
MRI spectroscopy is highly sensitive for lipid-soluble metabolites from UC-MSCs
Monday, 9 September 2013   by phys.org    
  News & More:
MR Spectroscopy Detects Biochemical Alterations in Pre-Invasive Breast Cancer Patients
Wednesday, 11 March 2015   by radiationtherapynews.com    
MR Spectroscopy Shows Differences in Brains of Preterm Infants
Monday, 25 November 2013   by www.digitaljournal.com    
Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder.
Wednesday, 16 March 2011   by leftbrainrightbrain.co.uk    
Magnetic resonance spectroscopy for breast cancer
Wednesday, 11 July 2007   by www.news-medical.net    
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Hybrid Spectroscopy
 
The combination of single volume spectroscopy and chemical shift imaging. The chemical shift measurement is performed over a selectively-excited volume of interest. Areas with strong distorting signal are not stimulated and therefore do not append signal to the spectra.
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Further Reading:
  News & More:
Near-IR Spectroscopy Performs Challenging Breast Imaging
Tuesday, 18 February 2014   by www.novuslight.com    
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Echo Planar SpectroscopyInfoSheet: - Sequences - 
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(EPS) See Spectroscopy.
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Gradient Echo SpectroscopyInfoSheet: - Sequences - 
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etc.MRI Resource Directory:
 - Spectroscopy pool -
 
(GES) See Gradient Echo Sequence and Spectroscopy.
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Single Volume Spectroscopy
 
(SVS) This method maps the metabolic information from the VOI in a spectrum. Single volume techniques are advantageous in case of pathological changes that cannot spatially be limited to a few VOI; by using local volume sensitive shim the local magnetic field inhomogeneity can be compensated.
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