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Magnetic Resonance Imaging MRI
 
(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 Anatomic Imaging of the Lumbar Spine  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Normal Dual Inversion Fast Spin-echo  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Breast MRI Images T2 And T1 Pre - Post Contrast  Open this link in a new window
 Anatomic Imaging of the Shoulder  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 
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Further Reading:
  Basics:
Bringing More Value to Imaging Departments With MRI
Friday, 4 October 2019   by www.itnonline.com    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
On the Horizon - Next Generation MRI
Wednesday, 23 October 2013   by thefutureofthings.com    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
  News & More:
High-resolution MRI enables direct imaging of neuronal activity - DIANA – direct imaging of neuronal activity
Friday, 18 November 2022   by physicsworld.com    
New MRI technique can 'see' molecular changes in the brain
Thursday, 5 September 2019   by medicalxpress.com    
How new MRI technology is transforming the patient experience
Tuesday, 14 May 2019   by newsroom.gehealthcare.com    
Metamaterials boost sensitivity of MRI machines
Thursday, 14 January 2016   by www.eurekalert.org    
MRI technique allows study of wrist in motion
Monday, 6 January 2014   by www.healthimaging.com    
New imaging technology promising for several types of cancer
Thursday, 29 August 2013   by medicalxpress.com    
MRI method for measuring MS progression validated
Thursday, 19 December 2013   by www.eurekalert.org    
MRI Resources 
Research Labs - Lung Imaging - Intraoperative MRI - NMR - MRI Technician and Technologist Schools - MRCP
 
Brain MRIForum -
related threadsMRI Resource Directory:
 - Brain MRI -
 
Brain imaging, magnetic resonance imaging of the head or skull, cranial magnetic resonance tomography (MRT), neurological MRI - they describe all the same radiological imaging technique for medical diagnostic.
Magnetic resonance imaging of the human brain includes the anatomic description and the detection of lesions. Special techniques like diffusion weighted imaging, functional magnetic resonance imaging (fMRI) and spectroscopy provide also information about the function and chemical metabolites of the brain. MRI provides detailed pictures of brain and nerve tissues in multiple planes without obstruction by overlying bones. Brain MRI is the procedure of choice for most brain disorders. It provides clear images of the brainstem and posterior brain, which are difficult to view on a CT scan. It is also useful for the diagnosis of demyelinating disorders (disorders such as multiple sclerosis (MS) that cause destruction of the myelin sheath of the nerve).
With this noninvasive procedure also the evaluation of blood flow and the flow of cerebrospinal fluid (CSF) is possible. Different MRA methods, also without contrast agents can show a venous or arterial angiogram. MRI can distinguish tumors, inflammatory lesions, and other pathologies from the normal brain anatomy. However, MRI scans are also used instead other methods to avoid the dangers of interventional procedures like angiography (DSA - digital subtraction angiography) as well as of repeated exposure to radiation as required for computed tomography (CT) and other X-ray examinations.
A (birdcage) bird cage coil achieves uniform excitation and reception and is commonly used to study the brain. Usually a brain MRI procedure includes FLAIR, T2 weighted and T1 weighted sequences in two or three planes.

See also Fetal MRI, Fluid Attenuation Inversion Recovery (FLAIR), Perfusion Imaging and High Field MRI.
See also Arterial Spin Labeling.
 
Images, Movies, Sliders:
 Brain MRI Images Axial T2  Open this link in a new window
      

 MRI of the Skull Base  Open this link in a new window
    
SlidersSliders Overview

 Anatomic Imaging of the Orbita  Open this link in a new window
      

 Brain MRI Images T1  Open this link in a new window
 MRI of the Brain Stem with Temoral Bone and Auditory System  Open this link in a new window
    
SlidersSliders Overview

 TOF-MRA Circle of Willis Inverted MIP  Open this link in a new window
    

 PCA-MRA 3D Brain Venography Colored MIP  Open this link in a new window
    

 
Medical-Ultrasound-Imaging.comA-Mode
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• View the DATABASE results for 'Brain MRI' (14).Open this link in a new window


• View the NEWS results for 'Brain MRI' (32).Open this link in a new window.
 
Further Reading:
  Basics:
New MRI technique offers faster diagnosis of multiple sclerosis
Monday, 1 February 2016   by medicalxpress.com    
Ultra-high-field MRI reveals language centres in the brain in much more detail
Tuesday, 28 October 2014   by medicalxpress.com    
A Dutch study has revealed that as many as 13% of healthy adults may have some type of undiagnosed abnormality in the brain.
Sunday, 4 November 2007   by www.news-medical.net:80    
  News & More:
MRI Reveals Significant Brain Abnormalities Post-COVID
Monday, 21 November 2022   by neurosciencenews.com    
Combining genetics and brain MRI can aid in predicting chances of Alzheimer's disease
Wednesday, 29 June 2022   by www.sciencedaily.com    
Roundup: How Even Mild COVID Can Affect the Brain; This Many Daily Steps Improves Longevity; and More
Friday, 11 March 2022   by baptisthealth.net    
A low-cost and shielding-free ultra-low-field brain MRI scanner
Tuesday, 14 December 2021   by www.nature.com    
Large International Study Reveals Spectrum of COVID-19 Brain Complications
Tuesday, 9 November 2021   by www.itnonline.com    
Brain MRI-Based Subtypes of MS Predict Disability Progression, Treatment Response
Thursday, 13 May 2021   by www.neurologyadvisor.com    
New MRI method improves detection of disease changes in the brain's network
Thursday, 11 June 2020   by www.compute.dtu.dk    
New NeuroCOVIDÂ Classification System Uses MRI to Categorize Patients
Friday, 12 June 2020   by www.diagnosticimaging.com    
New MRI technique can 'see' molecular changes in the brain
Thursday, 5 September 2019   by medicalxpress.com    
Talking therapy or medication for depression: Brain scan may help suggest better treatment
Monday, 27 March 2017   by www.newsnation.in    
MRI identifies brain abnormalities in chronic fatigue syndrome patients
Wednesday, 29 October 2014   by www.eurekalert.org    
MRIs Useful in Tracking Depression in MS Patients
Tuesday, 1 July 2014   by www.hcplive.com    
Contrast agent linked with brain abnormalities on MRI
Tuesday, 17 December 2013   by www.sciencecodex.com    
MRIs Reveal Signs of Brain Injuries Not Seen in CT Scans
Tuesday, 18 December 2012   by www.sciencedaily.com    
Iron Deposits in the Brain May Be Early Indicator of MS
Wednesday, 13 November 2013   by www.healthline.com    
Migraine Sufferers Have Thicker Brain Cortex
Tuesday, 20 November 2007   by www.medicalnewstoday.com    
MRI Resources 
Education - IR - PACS - Guidance - Contrast Enhanced MRI - MRI Technician and Technologist Schools
 
Cardiovascular ImagingMRI Resource Directory:
 - Cardiovascular Imaging -
 
Cardiovascular MR imaging includes the complete anatomical display of the heart with CINE imaging of all phases of the heartbeat. Ultrafast techniques make breath hold three-dimensional coverage of the heart in different cardiac axes feasible. Cardiac MRI provides reliable anatomical and functional assessment of the heart and evaluation of myocardial viability and coronary artery disease by a noninvasive diagnostic imaging technique.
Cardiovascular MRI offers potential advantages over radioisotopic techniques because it provides superior spatial resolution, does not use ionizing radiation, has no imaging orientations constraints and contrast resolution better than echocardiography. It also offers direct visualization and characterization of atherosclerotic plaques and diseased vessel walls and surrounding tissues in cardiovascular research.
MRI perfusion approaches measure the alteration of regional myocardial magnetic properties after the intravenous injection of contrast agents and assess the extent of injury after a myocardial infarction and the presence of myocardial viability with a technique based on late enhancement. Extracellular MRI contrast agents, like Gd-DTPA, accumulate only in irreversibly damaged myocardium after a time period of at least 10 minutes.
This type of patients may also have an implanted cardiac stent, bypass or a cardiac pacemaker and special caution should be observed on the MRI safety and the contraindications. While a number of coronary stents have been tested and reported to be MRI compatible, coronary stents must be assessed on an individual basis, with the medical team weighing the risks and benefits of the MRI procedure.

Cardiac MRI overview:
•
Myocardial perfusion imaging and viability
•
Calculation of ventricular volume, myocardial mass and wall thickness
•
Functional parameters
•
Description of a stenosis or aneurysma
•
Anatomical display of the heart, vessels and the surrounding tissue

Cardiovascular MRI has become one of the most effective noninvasive imaging techniques for almost all groups of heart and vascular disease.
 
Images, Movies, Sliders:
 Angulation of Cardiac Planes Cine Images of Septal Infarct  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Left Circumflex Ischemia First-pass Contrast Enhancement  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Delayed Myocardial Contrast Enhancement from Infarct  Open this link in a new window
 
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• View the DATABASE results for 'Cardiovascular Imaging' (18).Open this link in a new window


• View the NEWS results for 'Cardiovascular Imaging' (6).Open this link in a new window.
 
Further Reading:
  Basics:
Cardiac MRI - Technical Aspects Primer
Wednesday, 7 August 2002
Coronary Artery Disease: Combined Stress MR Imaging Protocol-One-Stop Evaluation of Myocardial Perfusion and Function1
   by radiology.rsnajnls.org    
A Guide To Cardiac Imaging
   by www.simplyphysics.com    
  News & More:
New Imaging Technique Reveals Different Heart Motions by Age, Gender
Thursday, 10 December 2009   by www.sciencedaily.com    
Searchterm 'MEDIC Technique' was also found in the following services: 
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Spectroscopy
 
Edward Purcell and Felix Bloch discovered the basic of spectroscopy in 1946 (see MRI History). Nuclear magnetic resonance spectroscopy (NMR Spectroscopy or MRS) is an analytical tool, based on nuclei that have a spin (nuclei with an odd number of neutrons and/or protons) like 1H, 13C, 17O, 19F, 31P etc.
Through nuclear magnetic principles as precession, chemical shift, spin spin coupling etc., the analysis of the content, purity, and molecular structure of a sample is possible. The spectrum produced by this process contains a number of peaks; the highs and the positions of these peaks allow the exact analysis. Unknown compounds can be matched against spectral libraries. Even very complex organic compounds as enzymes and proteins can be determined. For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different techniques available.
See Spectroscopic Imaging Techniques.
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• View the DATABASE results for 'Spectroscopy' (90).Open this link in a new window


• View the NEWS results for 'Spectroscopy' (3).Open this link in a new window.
 
Further Reading:
  Basics:
MR Spectroscopy May Help Avoid Invasive Procedures And Treatments For Recurrent Brain Lesions
Wednesday, 11 February 2009   by www.sciencedaily.com    
MRI spectroscopy is highly sensitive for lipid-soluble metabolites from UC-MSCs
Monday, 9 September 2013   by phys.org    
  News & More:
Pioneering MRI imaging method captures brain glucose metabolism without the need for administration of radioactive substances
Friday, 28 April 2023   by www.eurekalert.org    
New quantum sensing technique allows high-resolution nuclear magnetic resonance spectroscopy
Wednesday, 17 June 2020   by phys.org    
MR Spectroscopy Detects Biochemical Alterations in Pre-Invasive Breast Cancer Patients
Wednesday, 11 March 2015   by radiationtherapynews.com    
MR Spectroscopy Shows Differences in Brains of Preterm Infants
Monday, 25 November 2013   by www.digitaljournal.com    
Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder.
Wednesday, 16 March 2011   by leftbrainrightbrain.co.uk    
Magnetic resonance spectroscopy for breast cancer
Wednesday, 11 July 2007   by www.news-medical.net    
MRI Resources 
NMR - Chemistry - MR Myelography - Crystallography - Claustrophobia - Spine MRI
 
Spectroscopic Imaging Techniques
 
For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different spectroscopic imaging techniques available.
A short listing of the most frequent variations:
'One-dimensional NMR Spectroscopy (1D NMR) is attended to the spectra of (1H) Proton, 13Carbon etc., which in general is divided in continuous wave and pulse spectroscopy. General used to determine chemical structures. Proton nuclear magnetic resonance (1H-NMR) spectroscopy and carbon nuclear magnetic resonance (13C-NMR) spectroscopy are the most prominent techniques here.
'Two-dimensional NMR Spectroscopy' (2D NMR) is based on pulse spectroscopy. This technique is mostly used for the study of chemical interactions accompanied by magnetization transfer. Examples for more diversified spectroscopy techniques are based on homonuclear (COSY, TOCSY, 2D-INADEQUATE, NOESY, ROESY) or heteronuclear correlation (HSQC, HMQC, HMBC).
'Solid State NMR Spectroscopy' analyzes samples with little or no molecular mobility. Dipolar coupling and chemical shift anisotropy are the dominating nuclear physical effects here. Used for example in pharmaceutical analysis.
'Solution State NMR Spectroscopy' is a technique to analyze the structure of samples with a high degree of molecular mobility as polymers, proteins, nucleic acids etc.
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• View the DATABASE results for 'Spectroscopic Imaging Techniques' (2).Open this link in a new window

 
Further Reading:
  Basics:
Chemical Applications of NMR
   by hyperphysics.phy-astr.gsu.edu    
  News & More:
Automated analysis of the total choline resonance peak in breast proton magnetic resonance spectroscopy
Wednesday, 4 October 2023   by analyticalsciencejournals.onlinelibrary.wiley.com    
New Brain Imaging Technique Identifies Previously Undetected Epileptic Seizure Sites
Friday, 13 November 2015   by www.newswise.com    
Proton MR Spectroscopic Imaging without Water Suppression1
2000   by radiology.rsnajnls.org    
MRI Resources 
Crystallography - Breast Implant - Hospitals - Musculoskeletal and Joint MRI - Abdominal Imaging - Raman Spectroscopy
 
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