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Spectroscopic Imaging Techniques
 
For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different spectroscopic imaging techniques available.
A short listing of the most frequent variations:
'One-dimensional NMR Spectroscopy (1D NMR) is attended to the spectra of (1H) Proton, 13Carbon etc., which in general is divided in continuous wave and pulse spectroscopy. General used to determine chemical structures. Proton nuclear magnetic resonance (1H-NMR) spectroscopy and carbon nuclear magnetic resonance (13C-NMR) spectroscopy are the most prominent techniques here.
'Two-dimensional NMR Spectroscopy' (2D NMR) is based on pulse spectroscopy. This technique is mostly used for the study of chemical interactions accompanied by magnetization transfer. Examples for more diversified spectroscopy techniques are based on homonuclear (COSY, TOCSY, 2D-INADEQUATE, NOESY, ROESY) or heteronuclear correlation (HSQC, HMQC, HMBC).
'Solid State NMR Spectroscopy' analyzes samples with little or no molecular mobility. Dipolar coupling and chemical shift anisotropy are the dominating nuclear physical effects here. Used for example in pharmaceutical analysis.
'Solution State NMR Spectroscopy' is a technique to analyze the structure of samples with a high degree of molecular mobility as polymers, proteins, nucleic acids etc..
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Further Reading:
  Basics:
Chemical Applications of NMR
   by hyperphysics.phy-astr.gsu.edu    
  News & More:
New Brain Imaging Technique Identifies Previously Undetected Epileptic Seizure Sites
Friday, 13 November 2015   by www.newswise.com    
Proton MR Spectroscopic Imaging without Water Suppression1
2000   by radiology.rsnajnls.org    
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Spectroscopy
 
Edward Purcell and Felix Bloch discovered the basic of spectroscopy in 1946 (see MRI History). Nuclear magnetic resonance spectroscopy (NMR Spectroscopy or MRS) is an analytical tool, based on nuclei that have a spin (nuclei with an odd number of neutrons and/or protons) like 1H, 13C, 17O, 19F, 31P etc..
Through nuclear magnetic principles as precession, chemical shift, spin spin coupling etc., the analysis of the content, purity, and molecular structure of a sample is possible. The spectrum produced by this process contains a number of peaks; the highs and the positions of these peaks allow the exact analysis. Unknown compounds can be matched against spectral libraries. Even very complex organic compounds as enzymes and proteins can be determined. For the wide uses of NMR spectroscopy (from mineralogy to medicine) there is a variety of different techniques available.
See Spectroscopic Imaging Techniques.
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Further Reading:
  Basics:
MR Spectroscopy May Help Avoid Invasive Procedures And Treatments For Recurrent Brain Lesions
Wednesday, 11 February 2009   by www.sciencedaily.com    
MRI spectroscopy is highly sensitive for lipid-soluble metabolites from UC-MSCs
Monday, 9 September 2013   by phys.org    
  News & More:
MR Spectroscopy Detects Biochemical Alterations in Pre-Invasive Breast Cancer Patients
Wednesday, 11 March 2015   by radiationtherapynews.com    
MR Spectroscopy Shows Differences in Brains of Preterm Infants
Monday, 25 November 2013   by www.digitaljournal.com    
Proton Magnetic Resonance Spectroscopy and MRI Reveal No Evidence for Brain Mitochondrial Dysfunction in Children with Autism Spectrum Disorder.
Wednesday, 16 March 2011   by leftbrainrightbrain.co.uk    
Magnetic resonance spectroscopy for breast cancer
Wednesday, 11 July 2007   by www.news-medical.net    
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