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Magnetic
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Thursday, 29 July 2010 •• |
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MRI Resources |
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| Abdominal Imaging |  |
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General MRI of the abdomen can consist of T1 or T2 weighted spin echo, fast spin echo (FSE, TSE) or gradient echo sequences with fat suppression and contrast enhanced MRI techniques. The examined organs include liver, pancreas, spleen, kidneys, adrenals as well as parts of the stomach and intestine. Respiratory compensation and breath hold imaging is mandatory for a good image quality.
T1 weighted sequences are more sensitive for lesion detection than T2 weighted sequences at 0.5 T, while higher field strengths (greater than 1.0 T), T2 weighted and spoiled gradient echo sequences are used for focal lesion detection.
Gradient echo in phase T1 breath hold can be performed as a dynamic series with the ability to visualize the blood distribution. Phases of contrast enhancement include the capillary or arterial dominant phase for demonstrating hypervascular lesions, in liver imaging the portal venous phase demonstrates the maximum difference between the liver and hypovascular lesions, while the equilibrium phase demonstrates interstitial disbursement for edematous and malignant tissues.
Out of phase gradient echo imaging for the abdomen is a lipid-type tissue sensitive sequence and is useful for the visualization of focal hepatic lesions, fatty liver, haemochromatosis, adrenal lesions and renal masses.
The standards for abdominal MRI vary according to clinical sites based on sequence availability and MRI equipment.
Specific abdominal imaging coils and liver-specific contrast agents targeted to the reticuloendothelial system (RES) of the liver and spleen, improve the detection and localization of lesions in the liver.
See also Hepatobiliary Contrast Agents, Reticuloendothelial Contrast Agents, and Oral Contrast Agents.
For Ultrasound Imaging (USI) see Abdominal Ultrasound at US-TIP.com. |
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| Abdoscan® |  |
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| This superparamagnetic oral contrast agent consists of large iron oxide particles, coated with insoluble material. Abdoscan® particles have a mean diameter no less than 300 nm. Gastrointestinal superparamagnetic contrast agents are used for negative bowel enhancement.
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Drug Information and Specification |
| NAME OF COMPOUND |
Ferristene (USAN) oral magnetic particles (OMP) |
| DEVELOPER |
Amersham |
| CENTRAL MOIETY |
Fe2+/Fe3+ |
| CONTRAST EFFECT |
T2*, predominantly negative enhancement |
| RELAXIVITY |
T2 |
| PHARMACOKINETIC |
Gastrointestinal |
| CONCENTRATION |
23.4 Fe/200ml |
| PREPARATION |
Dissolve |
| INDICATION |
Bowel marking |
| DEVELOPMENT STAGE |
For sale |
| DISTRIBUTOR |
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| PRESENTATION |
Bags with powder |
| DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT! |
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MRI Resources |
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| The lowest possible temperature that can be obtained, at which all molecular motion discontinues. The unit is written as 0 K or 0 Kelvin, named after William Thomson, who developed the scale and became Lord Kelvin in 1892.
The analogous temperature in other units is:
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| | Component of the signal that yields in a symmetric, positive-valued line shape. |
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MRI Resources |
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| | [last update: 2010-07-26 01:53:30] |
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