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 'Frequency Encoding' 
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Incoherent Gradient Echo (Gradient Spoiled)InfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
The incoherent gradient echo (gradient spoiled) type of sequence uses a continuous shifting of the RF pulse to spoil the remaining transverse magnetization. The transverse magnetization is destroyed by a magnetic field gradient. This results in a T1 weighted image. Spoiling can be accomplished by RF or a gradient.
Gradient spoiling occurs after each echo by using strong gradients in the slice-select direction after the frequency encoding and before the next RF pulse. Because spins in different locations in the magnet thereby experience a variety of magnetic field strengths, they will precess at differing frequencies; as a consequence they will quickly become dephased. Magnetic field gradients are not very efficient at spoiling the transverse steady state. To be effective, the spins must be forced to precess far enough to become phased randomly with respect to the RF excitation pulse. In clinical MRI machines, the field gradients are set up in such a way that they increase and decrease relative to the center of the magnet; the magnetic field at the magnet 'isocenter' does not change.
The T1 weighting increases with the flip angle and the T2* weighting increases with echo time (TE). Typical repetition time (TR) are 30-500 ms and TE less than 15 ms.

See also Ernst Angle.
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MRI Resources 
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K-SpaceForum -
related threads
 
The k-space is an extension of the concept of Fourier space that is well known in imaging. In MR imaging the k-space is a temporary memory of the spatial frequency information in two or three dimensions of an object; the k-space is defined by the space covered by the phase and frequency encoding data.
The relation between K-space data and image data is the Fourier Transformation. The data acquisition matrix contains raw image data before the image processing. In 2 dimensional Fourier transformation imaging, a line of data corresponds to the digitized MRI signal at a particular phase encoding level. The position in k-space is directly related to the gradient across the object being imaged. By changing the gradient over time, the k-space data are sampled in a trajectory through Fourier space at each point until it is filled.

See also Spatial Frequency and Raw Data.
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• View the DATABASE results for 'K-Space' (65).Open this link in a new window

 
Further Reading:
  Basics:
K-space formulation of MRI
Tuesday, 22 March 2005   by www.ebyte.it    
The Basics of MRI
   by www.cis.rit.edu    
  News & More:
Optimal k-Space Sampling for Dynamic Contrast-Enhanced MRI with an Application to MR Renography
Thursday, 5 November 2009   by www.ncbi.nlm.nih.gov    
MRI Resources 
Process Analysis - Guidance - Knee MRI - NMR - Breast Implant - Directories
 
MRI History
 
•
Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
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In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
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Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
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In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
•
In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
•
In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
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1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
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In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
•
1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
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1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
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In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
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In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
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1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
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1988: Schering's MAGNEVIST gets its first approval by the FDA.
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In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
•
From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
•
 
Images, Movies, Sliders:
 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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• View the DATABASE results for 'MRI History' (6).Open this link in a new window


• View the NEWS results for 'MRI History' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MRI Resources 
MRI Physics - Societies - Raman Spectroscopy - MR Myelography - Mobile MRI Rental - Chemistry
 
Motion ArtifactInfoSheet: - Artifacts - 
Case Studies, 
Reduction Index, 
etc.MRI Resource Directory:
 - Artifacts -
 
Quick Overview
Please note that there are different common names for this artifact.
Artifact Information
NAME
Motion, phase encoded motion, instability, smearing
DESCRIPTION
Blurring and ghosting
REASON
Movement of the imaged object
HELP
Compensation techniques, more averages, anti spasmodic
Patient motion is the largest physiological effect that causes artifacts, often resulting from involuntary movements (e.g. respiration, cardiac motion and blood flow, eye movements and swallowing) and minor subject movements.
Movement of the object being imaged during the sequence results in inconsistencies in phase and amplitude, which lead to blurring and ghosting. The nature of the artifact depends on the timing of the motion with respect to the acquisition. Causes of motion artifacts can also be mechanical vibrations, cryogen boiling, large iron objects moving in the fringe field (e.g. an elevator), loose connections anywhere, pulse timing variations, as well as sample motion. These artifacts appear in the phase encoding direction, independent of the direction of the motion.
mri safety guidance
Image Guidance
Motion artifacts can be flipped 90° by swapping the phase//frequency encoding directions.
The artifacts can be reduced by using breath holding, cardiac synchronization or respiratory compensation techniques: triggering, gating, retrospective triggering or phase encoding artifact reduction. Flow effects can be reduced by using gradient moment nulling of the first order of flow, gradient moment rephasing or flow compensation, depending of the MRI system.
Peristaltic motion can be reduced with the intravenous injection of an anti-spasmodic (e.g. Buscopan).
By using multiple averages, respiratory motion can be reduced in the same way that multiple averages increase the signal to noise ratio. Noticeable motion averaging is seen when four averages are obtained, six averages are often as good as respiratory compensation techniques and higher averages will continue to improve image quality.
In some cases will help a presaturation of the anatomy that was generating the motion.

See also Phase Encoded Motion Artifact.
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• View the DATABASE results for 'Motion Artifact' (24).Open this link in a new window

 
Further Reading:
  Basics:
The Effects of Breathing Motion on DCE-MRI Images: Phantom Studies Simulating Respiratory Motion to Compare CAIPIRINHA-VIBE, Radial-VIBE, and Conventional VIBE
Tuesday, 7 February 2017   by www.kjronline.org    
  News & More:
Patient movement during MRI: Additional points to ponder
Tuesday, 5 January 2016   by www.healthimaging.com    
Motion-compensation of Cardiac Perfusion MRI using a Statistical Texture Ensemble(.pdf)
June 2003   by www.imm.dtu.dk    
MRI Resources 
Collections - Contrast Enhanced MRI - Knee MRI - Societies - MRI Technician and Technologist Career - MRI Technician and Technologist Schools
 
Multi Echo Data Image CombinationInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(MEDIC) MEDIC is a heavily T2* weighted spoiled gradient echo sequence with multiple echoes. MEDIC uses a series of identically phase encoded gradient echoes, sampled per line in k-space. Unipolar frequency encoding gradients are used to achieve flow compensation and to avoid off resonance effects. For each echo the magnitude images are reconstructed and postprocessed by using a sum of squares algorithm to improve the signal to noise ratio. The increased receiver bandwidth reduces the T2* effects and impairment of the spatial resolution.
The multi echo data image combination sequence is potentially useful in imaging of cartilage in joints.
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• View the DATABASE results for 'Multi Echo Data Image Combination' (2).Open this link in a new window

MRI Resources 
Mobile MRI - Service and Support - Case Studies - Stent - Manufacturers - Coils
 
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