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Longitudinal Relaxation Time
 
The T1 time constant, which determines the rate at which excited protons return to equilibrium within the lattice. The longitudinal relaxation time is a measure of the time taken for spinning protons to realign with the external magnetic field. The magnetization will grow after excitation from zero to a value of about 63% of its final value in a time of T1.
See also T1 Time.
 
Images, Movies, Sliders:
 Brain MRI Images T1  Open this link in a new window
 Sagittal Knee MRI Images T1 Weighted  Open this link in a new window
 
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Mangafodipir TrisodiumInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Short name: Mn-DPDP
This MRI contrast agent is a chelate complex of the paramagnetic metal ion manganese (Mn) and fodipir. Mn-DPDP (Teslascan) shortens the longitudinal relaxation time and is used for the T1 weighted enhancement of MR images. Mangafodipir trisodium accumulates after intravenous injection in the healthy tissue of the liver and improves the detection, localization, characterization, and evaluation of lesions of the liver, pancreas, but can also be used in cardiac MRI.
See also Hepatobiliary Chelates and Teslascan®.
The United States Food and Drug Administration (FDA) has granted marketing clearance 1997, to Nycomed Amersham’s MRI contrast medium. Nycomed/Amersham, now GE Healthcare markets the product under the trade name Teslascan®.

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Further Reading:
  Basics:
Teslascan Pharmacology, Pharmacokinetics, Studies, Metabolism - Mangafodipir - RxList Monograph
   by www.rxlist.com    
Mangafodipir (Systemic)
2003   by www.drugs.com    
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Diagnosis and staging of pancreatic cancer: comparison of mangafodipir trisodium-enhanced MR imaging and contrast-enhanced helical hydro-CT.
2002
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Spin Lattice Relaxation Time
 
(T1) The spin lattice relaxation time (also called longitudinal relaxation time and T1 Time) is a spin property, whereby the value changes between different tissues. By the spin lattice relaxation process, the longitudinal magnetization Mz achieve the equilibrium value Mz0. The T1 time constant is an exponential approach toward Mz0.
The equation for the magnetization at a time t will be (if at t=0 the longitudinal magnetization is Mz0):
Mz(t) = M0+(Mz (0) - Mz0) exp(t/T1)
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Further Reading:
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Electron Spin Resonance
   by hyperphysics.phy-astr.gsu.edu    
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MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
MULTIEXPONENTIAL PROTON SPIN-SPIN RELAXATION IN MAGNETIC RESONANCE IMAGING OF HUMAN BRAIN TUMORS
Friday, 26 March 1999   by www.dkfz-heidelberg.de    
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T1 Relaxation
 
The return to equilibrium (high energy protons returns to the low energy state) within the lattice is named the T1, spin lattice or longitudinal relaxation. During the time T1, the spinning protons realign with the external magnetic field with an exchange of their energy, resulting in heat. The value of the T1 time depends of the tissues ability for energy exchange. See also Longitudinal Relaxation Time.
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Further Reading:
  Basics:
Musculoskeletal MRI at 3.0 T: Relaxation Times and Image Contrast
Sunday, 1 August 2004   by www.ajronline.org    
  News & More:
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
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T1 TimeForum -
related threads
 
The T1 relaxation time (also called spin lattice or longitudinal relaxation time), is a biological parameter that is used in MRIs to distinguish between tissue types. This tissue-specific time constant for protons, is a measure of the time taken to realign with the external magnetic field. The T1 constant will indicate how quickly the spinning nuclei will emit their absorbed RF into the surrounding tissue.
As the high-energy nuclei relax and realign, they emit energy which is recorded to provide information about their environment. The realignment with the magnetic field is termed longitudinal relaxation and the time in milliseconds required for a certain percentage of the tissue nuclei to realign is termed 'Time 1' or T1. Starting from zero magnetization in the z direction, the z magnetization will grow after excitation from zero to a value of about 63% of its final value in a time of T1. This is the basic of T1 weighted images.
The T1 time is a contrast determining tissue parameter. Due to the slow molecular motion of fat nuclei, longitudinal relaxation occurs rather rapidly and longitudinal magnetization is regained quickly. The net magnetic vector realigns with B0 leading to a short T1 time for fat.
Water is not as efficient as fat in T1 recovery due to the high mobility of the water molecules. Water nuclei do not give up their energy to the lattice (surrounding tissue) as quickly as fat, and therefore take longer to regain longitudinal magnetization, resulting in a long T1 time.
See also T1 Weighted Image, T1 Relaxation, T2 Weighted Image, and Magnetic Resonance Imaging MRI.
 
Images, Movies, Sliders:
 Anatomic MRI of the Knee 2  Open this link in a new window
    
SlidersSliders Overview

 Breast MRI Images T2 And T1  Open this link in a new window
 Brain MRI Images T1  Open this link in a new window
      

 
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Further Reading:
  Basics:
IMAGE CONTRAST IN MRI(.pdf)
   by www.assaftal.com    
Magnetic resonance imaging - From Wikipedia, the free encyclopedia.
   by en.wikipedia.org    
  News & More:
Rockland Technimed: Tissue Viability Imaging
Saturday, 15 December 2007   by www.onemedplace.com    
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