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Coherent Gradient EchoInfoSheet: - Sequences - 
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Coherent gradient echo sequences can measure the free induction decay (FID), generated just after each excitation pulse or the echo formed prior to the next pulse. Coherent gradient echo sequences are very sensitive to magnetic field inhomogeneity. An alternative to spoiling is to incorporate residual transverse magnetization directly into the longitudinal steady state. These GRE sequences use a refocusing gradient in the phase encoding direction during the end module to maximize remaining transverse (xy) magnetization at the time when the next excitation is due, while the other two gradients are, in any case, balanced.
When the next excitation pulse is sent into the system with an opposed phase, it tilts the magnetization in the -a direction. As a result the z-magnetization is again partly tilted into the xy-plane, while the remaining xy-magnetization is tilted partly into the z-direction.
A fully refocused sequence with a properly selected and uniform f would yield higher signal, especially for tissues with long T2 relaxation times (high water content) so it is used in angiographic, myelographic or arthrographic examinations and is used for T2* weighting. The repetition time for this sequence has to be short. With short TR, coherent GE is also useable for breath hold and 3D technique. If the repetition time is about 200 msec there's no difference between spoiled or unspoiled GE. T1 weighting is better with spoiled techniques.
The common types include GRASS, FISP, FAST, and FFE.
The T2* component decreases with long TR and short TE. The T1 time is controlled by flip angle. The common TR is less than 50 ms and the common TE less than 15 ms
Other types have stronger T2 dependence but lower SNR. They include SSFP, CE-FAST, PSIF, and CE-FFE-T2.
Examples of fully refocused FID sequences are TrueFISP, bFFE and bTFE.
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    • Transverse Magnetization
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    • Free Induction Decay
    • Incoherent Gradient Echo (Gradient Spoiled)
    • Incoherent Gradient Echo (RF Spoiled)
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Gradient Recalled Echo SequenceInfoSheet: - Sequences - 
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The gradient recalled echo MRI sequence generates gradient echoes as a consequence of echo refocusing. The initial slice selective RF pulse applied to the tissue is less than 90° (typically rotation angles are between 10° and 90°). Immediately after this RF pulse, the spins begin to dephase.
Instead of a refocusing 180° RF pulse, reversing the gradient polarity produces a gradient echo. A negative phase encoding gradient and a dephasing frequency encoding gradient are used simultaneous. The switch on of the frequency encoding gradient produces an echo caused by refocusing of the dephasing, which is caused by the dephasing gradient.
TR and flip angle together control the T1, and TE control T2* weighting.
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• View the DATABASE results for 'Gradient Recalled Echo Sequence' (7).Open this link in a new window

 
Further Reading:
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Magnetic resonance imaging
   by www.scholarpedia.org    
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Rapid Excitation Magnetic Resonance ImagingInfoSheet: - Sequences - 
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(RE MRI) There are several approaches to speeding up the MRI data acquisition process by repeating the excitation by RF pulses in times short compared to T1, typically using small flip angles and gradient echo refocusing. When TR is also on the order of or shorter than T2, the repeated RF pulses will tend to refocus transverse magnetization remaining from prior excitations, setting up a condition of steady state free precession, and a dependence of signal strength (and image contrast) on both T1 and T2.
This can be modified in various ways, particularly:
1) to spoil the tendency to build up a steady state by reducing coherence between excitations, e.g. by variation of the phase or timing of consecutive RF pulses or of the strength of spoiler gradient pulses, thus increasing the relative dependence of signal strength on T1 or
2) acquire the signal when it is refocusing immediately prior to the next RF pulse, thus increasing the relative dependence of signal strength on T2.

See also Ultrafast Gradient Echo Sequence.
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• View the DATABASE results for 'Rapid Excitation Magnetic Resonance Imaging' (2).Open this link in a new window

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Spin Echo SequenceInfoSheet: - Sequences - 
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Spin Echo Timing Diagram (SE) The most common pulse sequence used in MR imaging is based of the detection of a spin or Hahn echo. It uses 90° radio frequency pulses to excite the magnetization and one or more 180° pulses to refocus the spins to generate signal echoes named spin echoes (SE).
In the pulse sequence timing diagram, the simplest form of a spin echo sequence is illustrated.
The 90° excitation pulse rotates the longitudinal magnetization (Mz) into the xy-plane and the dephasing of the transverse magnetization (Mxy) starts.
The following application of a 180° refocusing pulse (rotates the magnetization in the x-plane) generates signal echoes. The purpose of the 180° pulse is to rephase the spins, causing them to regain coherence and thereby to recover transverse magnetization, producing a spin echo.
The recovery of the z-magnetization occurs with the T1 relaxation time and typically at a much slower rate than the T2-decay, because in general T1 is greater than T2 for living tissues and is in the range of 100-2000 ms.
The SE pulse sequence was devised in the early days of NMR days by Carr and Purcell and exists now in many forms: the multi echo pulse sequence using single or multislice acquisition, the fast spin echo (FSE/TSE) pulse sequence, echo planar imaging (EPI) pulse sequence and the gradient and spin echo (GRASE) pulse sequence;; all are basically spin echo sequences.
In the simplest form of SE imaging, the pulse sequence has to be repeated as many times as the image has lines.
Contrast values:
PD weighted: Short TE (20 ms) and long TR.
T1 weighted: Short TE (10-20 ms) and short TR (300-600 ms)
T2 weighted: Long TE (greater than 60 ms) and long TR (greater than 1600 ms)
With spin echo imaging no T2* occurs, caused by the 180° refocusing pulse. For this reason, spin echo sequences are more robust against e.g., susceptibility artifacts than gradient echo sequences.

See also Pulse Sequence Timing Diagram to find a description of the components.
 
Images, Movies, Sliders:
 Shoulder Coronal T1 SE  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 Shoulder Axial T1 SE  Open this link in a new window
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• View the DATABASE results for 'Spin Echo Sequence' (24).Open this link in a new window

 
Further Reading:
  Basics:
Fast Spin Echo(.pdf)
Tuesday, 24 January 2006   by www.81bones.net    
Magnetic resonance imaging
   by www.scholarpedia.org    
FUNDAMENTALS OF MRI: Part I
   by www.e-radiography.net    
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New MR sequence helps radiologists more accurately evaluate abnormalities of the uterus and ovaries
Thursday, 23 April 2009   by www.eurekalert.org    
MRI techniques improve pulmonary embolism detection
Monday, 19 March 2012   by medicalxpress.com    
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Spoiler Gradient PulseInfoSheet: - Sequences - 
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Magnetic field gradient pulse applied to effectively remove transverse magnetization by producing a rapid variation of its phase along the direction of the gradient. This is done after the echo so that transverse magnetization is destroyed prior to the next excitation pulse, to spoil any remaining xy-magnetization or to refocus the xy-magnetization.
For example, when used to remove the unwanted signal resulting from an imperfect 180° refocusing RF pulse, a corresponding compensating gradient pulse may be applied prior to the refocusing RF pulse in order to avoid spoiling the desired transverse magnetization resulting from the initial excitation. Also called homospoil pulse.
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• View the DATABASE results for 'Spoiler Gradient Pulse' (6).Open this link in a new window

 
Further Reading:
  News & More:
Clinical evaluation of a speed optimized T2 weighted fast spin echo sequence at 3.0 T using variable flip angle refocusing, half-Fourier acquisition and parallel imaging
Wednesday, 25 October 2006
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