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Result : Searchterm 'Drug Information' found in 0 term [ ] and 26 definitions [ ]
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Searchterm 'Drug Information'
was also found in the following service of MR-TIP.com: |
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MRI Resources |
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| Artirem® |   |
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Artirem®, the arthrography-specific contrast agent for MRI is a dilute form of Dotarem® with a less concentration of Gd (1:200).
Artirem® has to be injected directly into the joints for better visualisation and delimitation, of the ligament and tendon structures in particular.
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Drug Information and Specification |
| NAME OF COMPOUND |
Gadoterate meglumine, Gd-DOTA |
| DEVELOPER |
Guerbet S.A. |
| CENTRAL MOIETY |
Gd2+ |
| CONTRAST EFFECT |
T1, Predominantly positive enhancement |
| RELAXIVITY |
r1=3.4, r2=4.8, B0=1.0T |
| PHARMACOKINETIC |
Intravascular, extracellular, renal excretion |
| CONCENTRATION |
0,0025 mmol/ml |
| PREPARATION |
Finished product |
| INDICATION |
Arthrography |
| DEVELOPMENT STAGE |
For sale |
| DISTRIBUTOR |
See below |
| PRESENTATION |
Pre-filled syringes of 20 mL |
| DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT! |
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Searchterm 'Drug Information'
was also found in the following service of MR-TIP.com: |
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| Clariscan™ |   |
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An iron-based contrast agent with large molecular size, which prevents diffusion into body tissues and will be developed for MR imaging of the liver (taken up by macrophages), tumor microvasculature and microvessel permeability. The blood half live of the particles with 11-20 nm diameter is 3-4 hours.
At this time the development of Clariscan™ is discontinued.
See also NC100150 Injection and Ultrasmall Superparamagnetic Iron Oxide.
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Drug Information and Specification |
| NAME OF COMPOUND |
Feruglose, PEG-feron, USPIO, NC100150
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| DEVELOPER |
Amersham Health |
| CENTRAL MOIETY |
Fe |
| CONTRAST EFFECT |
T2, Predominantly negative enhancement |
| RELAXIVITY |
R1=20, R2=35, B0=0.5T |
| PHARMACOKINETIC |
Intravascular |
| OSMOLALITY |
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| CONCENTRATION |
29.8 mg Fe/mL |
| PREPARATION |
Suspend in an isotonic glucose solution |
| INDICATION |
Cardiovascular |
| DEVELOPMENT STAGE |
? |
| DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT! |
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Further Reading: |
Basics:
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MRI Resources |
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| Combidex® |   |
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Combidex® is the brand name (same as Sinerem®) for an ultrasmall superparamagnetic iron oxide (USPIO) in the development pipeline to detect metastatic disease in lymph nodes. Metastatic lymph nodes show less uptake of this MRI contrast agent, which results in less signal decrease and allows the differentiation of normal lymph nodes from normal-sized, metastatic nodes.
See also Ferumoxtran, and Classifications, Characteristics, etc.
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Drug Information and Specification |
| NAME OF COMPOUND |
Ferumoxtran, USPIO, AMI-227 |
| DEVELOPER |
AMAG Pharmaceuticals, Inc. |
| CENTRAL MOIETY |
Fe3+/Fe2+ |
| CONTRAST EFFECT |
T1, predominantly T2 |
| RELAXIVITY |
r1=25, r2=160, B0=0.47T, r1=23.3, r2=48.9, B0=0.47T |
| PHARMACOKINETIC |
Vascular, lymph v. hepatocyte (AG-USPIO) |
| OSMOLALITY |
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| CONCENTRATION |
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| DOSAGE |
2.6 mg Fe/kg |
| PREPARATION |
Suspend in an isotonic glucose solution |
| INDICATION |
Lymph node, (MR angiography vascular, staging of RES-directed liver diseases) |
| DEVELOPMENT STAGE |
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| DISTRIBUTOR |
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| PRESENTATION |
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| DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT! |
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Further Reading: |
Basics:
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| | | | | •• There is 1 news about 'Combidex®'. | |
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Searchterm 'Drug Information'
was also found in the following service of MR-TIP.com: |
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| Dotarem® |   |
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Dotarem® is a paramagnetic ionic MRI contrast agent. Extracellular contrast agents like Dotarem®, can be bolus injected because of the relatively low rate of side effects. This contrast medium is useable to enhance signal intensity in magnetic resonance imaging for intracranial and spinal lesions with an abnormal blood brain barrier or abnormal vascularity, and in whole body imaging.
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Drug Information and Specification |
| NAME OF COMPOUND |
Gadoterate meglumine, Gd-DOTA |
| DEVELOPER |
Guerbet S.A. |
| CENTRAL MOIETY |
Gd2+ |
| CONTRAST EFFECT |
T1, Predominantly positive enhancement |
| RELAXIVITY |
r1=3.4, r2=4.8, B0=1.0T |
| PHARMACOKINETIC |
Intravascular, extracellular, renal excretion |
| OSMOLALITY |
1350 mosm/kgH2O |
| CONCENTRATION |
0.5 mol/L |
| DOSAGE |
0.1 mmol/kg / 0.2mL/kg |
| PREPARATION |
Finished product |
| INDICATION |
Neuro/whole body |
| DEVELOPMENT STAGE |
For sale |
| DISTRIBUTOR |
See below |
| PRESENTATION |
Vials of 5, 10, 15, 20mL Pre-filled syringes of 15 and 20 mL |
| DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING
PACKAGE INSERT! |
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Distribution Information |
| TERRITORY |
TRADE NAME |
DEVELOPMENT STAGE |
DISTRIBUTOR |
| EU |
Dotarem® |
for sale |
Guerbet S.A. |
| France, Switzerland |
Artirem® |
for sale |
Guerbet S.A. |
| Australia |
Dotarem® |
for sale |
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Further Reading: |
Basics:
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News & More:
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MRI Resources |
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