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 'Drug Information' 
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Result : Searchterm 'Drug Information' found in 0 term [] and 26 definitions []
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Searchterm 'Drug Information' was also found in the following services of MR-TIP.com:  
News  (2)   Resources  (2)  
 
Abdoscan®InfoSheet: - Contrast Agents - Intro, Overview, Characteristics, Types of, etc.MRI Resource Directory: - Contrast Agents -
 
This superparamagnetic oral contrast agent consists of large iron oxide particles, coated with insoluble material. Abdoscan® particles have a mean diameter no less than 300 nm. Gastrointestinal superparamagnetic contrast agents are used for negative bowel enhancement.

Drug Information and Specification
NAME OF COMPOUND Ferristene (USAN) oral magnetic particles (OMP)
DEVELOPER Amersham
CENTRAL MOIETY Fe2+/Fe3+
CONTRAST EFFECT T2*, predominantly negative enhancement
RELAXIVITY T2
PHARMACOKINETIC Gastrointestinal
CONCENTRATION 23.4 Fe/200ml
PREPARATION Dissolve
INDICATION Bowel marking
DEVELOPMENT STAGE For sale
DISTRIBUTOR
PRESENTATION Bags with powder
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Further Reading:
  Basics:
Progress Report: MRI Contrast Agents and AtherosclerosisOpen this link in a new window
2006   by www.ncbi.nlm.nih.gov    
  News & More:
CONTRAST AGENTS IN MRI(.pdf)Open this link in a new window
Market for GI MRI contrast agents may get crowded as approvals nearOpen this link in a new window
Wednesday, 8 January 1997   by www.consultantlive.com    
MRI Resources  
Pediatric and Fetal MRI - MRI Technician and Technologist Schools - Nerve Stimulator - Absorption and Emission - Safety Training - Pacemaker
 
Artirem®InfoSheet: - Contrast Agents - Intro, Overview, Characteristics, Types of, etc.MRI Resource Directory: - Contrast Agents -
 
Artirem®, the arthrography-specific contrast agent for MRI is a dilute form of Dotarem® with a less concentration of Gd (1:200). Artirem® has to be injected directly into the joints for better visualisation and delimitation, of the ligament and tendon structures in particular.

Drug Information and Specification
NAME OF COMPOUND Gadoterate meglumine, Gd-DOTA
DEVELOPER Guerbet S.A.
CENTRAL MOIETY Gd2+
CONTRAST EFFECT T1, Predominantly positive enhancement
RELAXIVITY r1=3.4, r2=4.8, B0=1.0T
PHARMACOKINETIC Intravascular, extracellular, renal excretion
CONCENTRATION 0,0025 mmol/ml
PREPARATION Finished product
INDICATION Arthrography
DEVELOPMENT STAGE For sale
DISTRIBUTOR See below
PRESENTATION Pre-filled syringes of 20 mL
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!

Distribution Information
TERRITORY TRADE NAME DEVELOPMENT
STAGE		 DISTRIBUTOR
EU Dotarem® for sale Guerbet S.A.
France, Switzerland Artirem® for sale Guerbet S.A.
Australia Dotarem® for sale

Searchterm 'Drug Information' was also found in the following services of MR-TIP.com:  
News  (2)   Resources  (2)  
 
Clariscan™InfoSheet: - Contrast Agents - Intro, Overview, Characteristics, Types of, etc.MRI Resource Directory: - Contrast Agents -
 
An iron-based contrast agent with large molecular size, which prevents diffusion into body tissues and will be developed for MR imaging of the liver (taken up by macrophages), tumor microvasculature and microvessel permeability. The blood half live of the particles with 11-20 nm diameter is 3-4 hours.
At this time the development of Clariscan™ is discontinued.
See also NC100150 Injection and Ultrasmall Superparamagnetic Iron Oxide.

Drug Information and Specification
NAME OF COMPOUND Feruglose, PEG-feron, USPIO, NC100150
DEVELOPER Amersham Health
CENTRAL MOIETY Fe
CONTRAST EFFECT T2, Predominantly negative enhancement
RELAXIVITY R1=20, R2=35, B0=0.5T
PHARMACOKINETIC Intravascular
OSMOLALITY
CONCENTRATION 29.8 mg Fe/mL
PREPARATION Suspend in an isotonic glucose solution
INDICATION Cardiovascular
DEVELOPMENT STAGE ?
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!


Further Reading:
  Basics:
Progress Report: MRI Contrast Agents and AtherosclerosisOpen this link in a new window
2006   by www.ncbi.nlm.nih.gov    
  News & More:
Utility of NC100150 Injection in Cardiac MRI(.pdf)Open this link in a new window
May 2002   by www.academicradiology.com       [Free, but registration is required.]
Comparison between Gadopentetate and Feruglose (Clariscan™)-enhanced MR-Mammography:(.pdf)Open this link in a new window
July 2002   by www.academicradiology.com       [Free, but registration is required.]
MRI Resources  
Spectroscopy pool - Libraries - Shoulder MRI - Implant and Prosthesis pool - Resources - General
 
Combidex®InfoSheet: - Contrast Agents - Intro, Overview, Characteristics, Types of, etc.MRI Resource Directory: - Contrast Agents -
 
Combidex® is the brand name (same as Sinerem®) for an ultrasmall superparamagnetic iron oxide (USPIO) in the development pipeline to detect metastatic disease in lymph nodes. Metastatic lymph nodes show less uptake of this MRI contrast agent, which results in less signal decrease and allows the differentiation of normal lymph nodes from normal-sized, metastatic nodes.
See also Ferumoxtran, and Classifications, Characteristics, etc.

Drug Information and Specification
NAME OF COMPOUND Ferumoxtran, USPIO, AMI-227
DEVELOPER AMAG Pharmaceuticals, Inc.
CENTRAL MOIETY Fe3+/Fe2+
CONTRAST EFFECT T1, predominantly T2
RELAXIVITY r1=25, r2=160, B0=0.47T, r1=23.3, r2=48.9, B0=0.47T
PHARMACOKINETIC Vascular, lymph v. hepatocyte (AG-USPIO)
OSMOLALITY
CONCENTRATION
DOSAGE 2.6 mg Fe/kg
PREPARATION Suspend in an isotonic glucose solution
INDICATION Lymph node, (MR angiography vascular, staging of RES-directed liver diseases)
DEVELOPMENT STAGE
DISTRIBUTOR
PRESENTATION
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!


Further Reading:
  Basics:
Combidex®Open this link in a new window
   by www.amagpharma.com    
Progress Report: MRI Contrast Agents and AtherosclerosisOpen this link in a new window
2006   by www.ncbi.nlm.nih.gov    
  News & More:
Ultrasmall Superparamagnetic IronOxide–enhanced MR Imaging of AtheroscleroticPlaque in Hyperlipidemic Rabbits, RUEHM ET AL Academic Radiology, Vol 9, Suppl 1, page 143(.pdf)Open this link in a new window
2002   by www.academicradiology.com       [Free, but registration is required.]
Superparamagnetic Iron Oxide–enhanced MR Imaging of Head and Neck Lymph Nodes1(.pdf)Open this link in a new window
2002
 •• There is 1 news about 'Combidex®'.
Searchterm 'Drug Information' was also found in the following services of MR-TIP.com:  
News  (2)   Resources  (2)  
 
Dotarem®InfoSheet: - Contrast Agents - Intro, Overview, Characteristics, Types of, etc.MRI Resource Directory: - Contrast Agents -
 
Dotarem® is a paramagnetic ionic MRI contrast agent. Extracellular contrast agents like Dotarem®, can be bolus injected because of the relatively low rate of side effects. This contrast medium is useable to enhance signal intensity in magnetic resonance imaging for intracranial and spinal lesions with an abnormal blood brain barrier or abnormal vascularity, and in whole body imaging.

Drug Information and Specification
NAME OF COMPOUND Gadoterate meglumine, Gd-DOTA
DEVELOPER Guerbet S.A.
CENTRAL MOIETY Gd2+
CONTRAST EFFECT T1, Predominantly positive enhancement
RELAXIVITY r1=3.4, r2=4.8, B0=1.0T
PHARMACOKINETIC Intravascular, extracellular, renal excretion
OSMOLALITY 1350 mosm/kgH2O
CONCENTRATION 0.5 mol/L
DOSAGE 0.1 mmol/kg / 0.2mL/kg
PREPARATION Finished product
INDICATION Neuro/whole body
DEVELOPMENT STAGE For sale
DISTRIBUTOR See below
PRESENTATION Vials of 5, 10, 15, 20mL
Pre-filled syringes of 15 and 20 mL
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!

Distribution Information
TERRITORY TRADE NAME DEVELOPMENT
STAGE		 DISTRIBUTOR
EU Dotarem® for sale Guerbet S.A.
France, Switzerland Artirem® for sale Guerbet S.A.
Australia Dotarem® for sale

Further Reading:
  Basics:
ADEC 208th meeting recommendationsOpen this link in a new window
   by www.tga.gov.au    
CONTRAST AGENTS IN MRI(.pdf)Open this link in a new window
  News & More:
Arterial Concentration Profiles of Two Blood PoolAgents and Gd-DOTA after IntravenousInjection in Rabbits, COROT ET AL Academic Radiology, Vol 9, Suppl 1(.pdf)Open this link in a new window
2002   by www.academicradiology.com       [Free, but registration is required.]
NEPHROGENIC SYSTEMIC FIBROSIS: AN UNCOMMON AND DEBILITATING DISEASE POSSIBLY ASSOCIATED WITH GADOLINIUM CHELATES(.pdf)Open this link in a new window
Friday, 21 December 2007   by www.guerbet.com    
MRI Resources  
Education - Used and Refurbished MRI Equipment - Foren, Newsgroups - Cardiovascular Imaging - Process Analysis - Distributors
 
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