With an open configuration MRI system neurosurgical procedures can be performed using image guidance. Open MRI can be used to guide interventional treatments or procedures, such as a biopsy.
Intraoperative MRI allows lesions to be precisely localized and targeted. Constantly updated images, correlated with images obtained pre-operatively, help to eliminate errors that can arise during framed and frameless stereotactic surgery when anatomic structures alter their position due to shifting or displacement of, e.g. brain parenchyma.
Intraoperative MRI can help with the identification of normal structures, such as blood vessels and is helpful in optimizing surgical approaches, achieving complete resection of intracerebral lesions, determining tumor margins and monitoring potential intraoperative complications.

For a contrast enhanced MR angiography of the peripheral blood vessels, the patient reclines on a moveable table that moves under the MR machine to provide images of the abdomen, upper and lower legs in one procedure. A time optimized 3D gradient echo protocol with contrast agent and tabletop movement in several stages is used.

(MSOFT) See Off Resonance and Fat Suppression.

(RE MRI) There are several approaches to speeding up the MRI data acquisition process by repeating the excitation by RF pulses in times short compared to T1, typically using small flip angles and gradient echo refocusing. When TR is also on the order of or shorter than T2, the repeated RF pulses will tend to refocus transverse magnetization remaining from prior excitations, setting up a condition of steady state free precession, and a dependence of signal strength (and image contrast) on both T1 and T2.
This can be modified in various ways, particularly:
1) to spoil the tendency to build up a steady state by reducing coherence between excitations, e.g. by variation of the phase or timing of consecutive RF pulses or of the strength of spoiler gradient pulses, thus increasing the relative dependence of signal strength on T1 or
2) acquire the signal when it is refocusing immediately prior to the next RF pulse, thus increasing the relative dependence of signal strength on T2.

See also Ultrafast Gradient Echo Sequence.

(3D MRA) The 3D angiography technique can be applied to focus on fast flowing (arterial) blood and to visualize small tortuous vessels. 3D TOF images are less sensitive to turbulent flow artifacts. The advantage of this approach is that the signal, acquired from the entire volume has an increased signal to noise ratio. Slices are defined by a second phase encoded axis, which divides the volume into 'partitions'. 3D TOF MRA is acquired with 3D FT slabs or multiple overlapping thin 3D FT slabs (MOTSA) depending on the coverage required and the range of flow-velocities under examination.
Such 3D techniques can provide equal spatial resolution along all three axes, i.e. be 'isotropic', or the partition thickness can be greater or less than the in plane spatial resolution in which case can be said to be 'anisotropic'. The circle of Willis, anatomy as well as its fast arterial flow, lends itself well to both 3D TOF and 2D or 3D phase contrast angiography.