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 'Imagent GI' 
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Result : Searchterm 'Imagent GI' found in 1 term [] and 2 definitions []
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MRI Resources 
Research Labs - Contrast Agents - Raman Spectroscopy - Functional MRI - Diffusion Weighted Imaging - Coils
 
Imagent GIInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Perflubron® is a perfluorochemical for use as an oral contrast agent. Due to its insolubility in water it does not mix with intestinal secretions; thus bowel lumina appear homogeneously dark on MR images when Perflubron® replaces bowel contents. Filled bowel loops appear black with all pulse sequences because the contrast agent lacks mobile protons.
It is commercially available as Imagent GI. Because rapid transit through the gastrointestinal tract it reaches the rectum within 30 to 40 minutes in most patients. MR imaging of the upper abdominal region should begin within 15 minutes and of the pelvic region 15 to 60 minutes after ingestion of perflubron.
See also Classifications, Characteristics, etc.

Drug Information and Specification
NAME OF COMPOUND Perfluoroctylbromide
DEVELOPER Alliance
CENTRAL MOIETY
CONTRAST EFFECT Negative enhancement
RELAXIVITY Proton density reduction, signal void
PHARMACOKINETIC Gastrointestinal
OSMOLALITY
CONCENTRATION Water immiscible liquid
DOSAGE 9 mL per kg of body weight
PREPARATION Finished product
INDICATION Bowel marking
DEVELOPMENT STAGE For sale
DISTRIBUTOR See below
PRESENTATION Bottle of 200cc
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT

Distribution Information
TERRITORY TRADE NAME DEVELOPMENT
STAGE
DISTRIBUTOR
USA Imagent GI® for sale Alliance Pharmaceutical Corp.

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Further Reading:
  News & More:
Slumping MRI market prompts Alliance to halt GI contrast agent effort
Wednesday, 28 September 1994   by www.searchmedica.com    
MRI Resources 
Pregnancy - Sequences - Coils - Hospitals - Anatomy - Implant and Prosthesis pool
 
Alliance Pharmaceutical Corp.MRI Resource Directory:
 - Manufacturers -
 
www.allp.htm

California-based research and development company. Alliance has several patents regarding "microbubble" compositions such as Imagent® that are intended to enhance ultrasound imaging and Imagent GI as a gastrointestinal MRI contrast agent. Another product is Oxygent™, a synthetic "blood substitute".


Product Information
TRADE NAME
(LOCAL DISTRIBUTION)
FOR SALE FOR SALE /
DEVELOPMENT
DEVELOPMENT
Imagent GI

Contact Information
MAIL Alliance Pharmaceutical Corp.
6175 Lusk Blvd.
San Diego, CA 92121
USA
PHONE +1-858-410-5200
FAX +1-858-410-5161
E-MAIL corpcom@allp.com
ONLINE www.allp.com

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Further Reading:
  Basics:
Slumping MRI market prompts Alliance to halt GI contrast agent effort
Wednesday, 28 September 1994   by www.searchmedica.com    
MRI Resources 
Artifacts - Pediatric and Fetal MRI - MRI Technician and Technologist Career - Open Directory Project - Fluorescence - Homepages
 
PerfluorochemicalsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Perfluorochemicals are fluorinated organic compounds. Perfluorochemicals can be used in gastrointestinal imaging as a negative contrast agent to reduce signal in the intestine. The MRI signal reduction is caused by the absence of mobile protons.
Perfluoroctylbromide (PFOB)(C8F17Br) is suitable for gastrointestinal use in humans; perfluorononane has been tested in animal models. PFOB is commercially available as Perflubron® (Imagent GI, Alliance). Benefits of this type of contrast media are biologically inertia, immiscibility with water, and a fast transit through the small intestine caused by low surface tension.
Fluosol-DA, a perfluorochemical emulsion has been tested in mice as a tumor specific agent for 19F-MRI.
See also Classifications, Characteristics, etc.
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Further Reading:
  Basics:
Pulmonary applications of perfluorochemical liquids: Ventilation and beyond
2005   by cryoeuro.eu:8080    
Artifical Blood
   by medind.nic.in    
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
MRI Resources 
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