UltraSound - Technology Information PortalThursday, 16 August 2018
Info
  Sheets



Out-
      side
 




 
 'Microbubble Shell' 
SEARCH FOR   
 
  12345ABCDEFGHIJKLMNOPQRSTUVWZ
Result : Searchterm 'Microbubble Shell' found in 1 term [] and 4 definitions [], (+ 14 Boolean[] results)
1 - 5 (of 19)     next
Result Pages : [1]  [2 3 4]
US Resources  
Used and Refurbished UltraSound Equipment - Gall Bladder - Modes - Distributors - Image Libraries - Liver
 
Microbubble ShellInfoSheet: - Contrast Agents - 
Intro, 
Historical Development, 
Microbubbles,
etc.MRI Resource Directory:<br> - Contrast Agents -
 
A microbubble shell, designed to reduce diffusion into the blood, can be stiff (e.g., denatured albumin) or more flexible (phospholipid), varying in thickness from 10–200 nm.
The shell stabilizes against dissolution and coalescence with additional materials at the gas-liquid interface. This material can be an elastic solid shell that enhances stability by supporting a strain to counter the effect of surface tension. Also a surfactant, or a combination of two or more, improves the stability by a high reduction of the surface tension at the interface. Current ultrasound contrast agents are micron-sized bubbles with a stabilizing shell.
spacer
• Related Searches:
    • Bubble Destruction
    • Bubble Rupture
    • Contrast Agent Particles
    • Bubble Specific Imaging
    • Contrast Enhanced Ultrasound

 Further Reading:
  Basics:
Optical observation of lipid- and polymer-shelled ultrasound microbubble contrast agentsOpen this link in a new window
   by escholarship.org    
  News & More:
Acoustic Signatures of Submicron Contrast Agents(.pdf)Open this link in a new window
Wednesday, 3 March 2004   by www.ncbi.nlm.nih.gov    
Bio-effects of ultrasound contrast agents in daily clinical practice: fact or fiction?(.pdf)Open this link in a new window
Monday, 30 April 2007   by eurheartj.oxfordjournals.org    
US Resources  
Ultrasound Therapy - Thyroid - Resources - Obstetric - 4d UltraSound - Research Labs
 
Bubble DestructionMRI Resource Directory:<br> - Contrast Agents -
 
Bubble destruction describes the microbubble shell rupture by ultrasound pulses. The bubble destruction increases with increasing peak negative pressure and decreasing frequency. The mechanical index is an indicator for the effectiveness of microbubble destruction. Contrast enhanced ultrasound relies on bubble rupture to detect bubbles in small vessels.
See also Negative Bolus.
spacer

US Resources  
Online Books - Vascular - Equipment and Parts - Prenatal - Intravascular - Image Quality
 
MP1950InfoSheet: - Contrast Agents - 
Intro, 
Historical Development, 
Microbubbles,
etc.MRI Resource Directory:<br> - Contrast Agents -
 
From Mallinckrodt Inc
MP1950 is an experimental thin lipid-shelled ultrasound contrast agent with a decafluorobutane gas core. MP1950 has a monolayer lipid microbubble shell with a thickness in the order of a few nanometers.
spacer

 Further Reading:
  Basics:
Bio-effects of ultrasound contrast agents in daily clinical practice: fact or fiction?(.pdf)Open this link in a new window
Monday, 30 April 2007   by eurheartj.oxfordjournals.org    
  News & More:
The role of ultrasound in molecular imaging(.pdf)Open this link in a new window
2003   by bjr.birjournals.org    
US Resources  
Directories - Developers - Intravascular - Ultrasound Gel - Renal - Examinations
 
Ultrasonic Contrast AgentsMRI Resource Directory:<br> - Contrast Agents -
 
(UCA / USCA) Ultrasonic contrast agents, also called ultrasound contrast agents, are encapsulated bubbles on the order of 1?10 µm in diameter. These gas bubbles are injected into the blood stream in order to increase blood/ tissue contrast during an ultrasonogram. These microbubbles are filled with air or a gas with a lower solubility in blood than air, such as perfluorochemicals. The microbubble shell consists of albumin, phospholipid, or other material and encapsulates the gas core. Due to this construction, ultrasonic contrast agents are highly compressible, and have a high echogenicity.
See also Ultrasound Contrast Agent Safety.
spacer

• View the news results for 'Ultrasonic Contrast Agents' (1).



US Resources  
DICOM - UltraSound Reimbursement - Safety - Ultrasound Guided Interventions - Journals - Pelvic
 
Ultrasound Contrast AgentsInfoSheet: - Contrast Agents - 
Intro, 
Historical Development, 
Microbubbles,
etc.MRI Resource Directory:<br> - Contrast Agents -
 
(UCA / USCA) Ultrasonography is the most commonly performed diagnostic imaging procedure. The introduction of sonographic contrast media into routine practice modifies the use of ultrasound in a variety of clinical applications. USCAs consist of microbubbles filled with air or gases and can be classified according to their pharmacokinetics. Among the blood pool agents, transpulmonary ultrasound contrast agents offer higher diagnostic potential compared to agents that cannot pass the pulmonary capillary bed after a peripheral intravenous injection. In addition to their vascular phase, some USCAs can exhibit a tissue- or organ-specific phase.
The sonogram image quality is improved either by decreasing the reflectivity of the undesired interfaces or by increasing the backscattered echoes from the desired regions.

Different types of ultrasound contrast agents:
point tissue contrast agents;
point contrast agents for vascular enhancement;
point agents for targeted contrast imaging.
Ultrasound contrast agents act as echo-enhancers, because of the high different acoustic impedance at the interface between gas and blood. The enhanced echo intensity is proportional to the change in acoustical impedance as the sound beam crosses from the blood to the gas in the bubbles.

The ideal qualities of an ultrasound contrast agent:
point high echogenicity;
point low attenuation;
point low blood solubility;
point low diffusivity;
point ability to pass through the pulmonary capillary bed;
point lack of biological effects with repeat doses.
A typical ultrasound contrast agent consists of a thin flexible or rigid shell composed of albumin, lipid, or polymer confining a gas such as nitrogen, or a perfluorocarbon. The choice of the microbubble shell and gas has an important influence on the properties of the agent.
Current generations of microbubbles have a diameter from 1 µm to 5 µm. The success of these agents is mostly dependent on the small size and on the stability of their shell, which allows passage of the microbubbles through the pulmonary circulation. Microbubbles must be made smaller than the diameter of capillaries or they would embolize and be ineffective and perhaps even dangerous.
The reflectivity of these microbubbles is proportional to the fourth power of a particle diameter but also directly proportional to the concentration of the contrast agent particles themselves.
Ultrasound contrast agents produce unique acoustic signatures that allow to separate their signal from tissue echoes and to depict whether they are moving or stationary. This enables the detection of capillary flow and of targeted microbubbles that are retained in tissues such as normal liver.
The new generation of contrast media is characterized by prolonged persistence in the vascular bed which provides consistent enhancement of the arterial Doppler signal. Contrast agents make it also possible to perform dynamic and perfusion studies. Targeted contrast imaging agents are for example taken up by the phagocytic cell systems and thus have liver//spleen specific effects.
See also Ultrasound Contrast Agent Safety, Adverse Reaction, Tissue-Specific Ultrasound Contrast Agent, and Bubble Specific Imaging.
Radiology-tip.comContrast Agents
spacer
Radiology-tip.comContrast Agents
spacer

• View the news results for 'Ultrasound Contrast Agents' (2).



 Further Reading:
  Basics:
Guidelines and Good Clinical Practice Recommendations for Contrast Enhanced Ultrasound (CEUS)Open this link in a new window
2008   by www.efsumb.org    
Science to Practice: Blood Flow Quantification with Contrast-enhanced USOpen this link in a new window
   by radiology.rsna.org    
  News & More:
More stable contrast media expand the ultrasound spectrumOpen this link in a new window
   by www.european-hospital.com    
Modeling and Characterization of Ultrasound Contrast AgentsOpen this link in a new window
   by home.online.no    
US Resources  
Gall Bladder - PACS - UltraSound Technician and Technologist Career - Devices Machines Scanners Systems - Ultrasound Therapy - RIS
 
Related Searches:
 • History of Ultrasound Contrast Agents
 • Cavitation
 • Bubble Specific Imaging
 • Target Strength
 • Bubble Destruction
SEARCH FOR   
 
  12345ABCDEFGHIJKLMNOPQRSTUVWZ
     1 - 5 (of 19)     next
Result Pages : [1]  [2 3 4]
 Random Page
 
Share This Page
FacebookTwitterLinkedIn

US-TIP    
Community   
User
Pass
Forgot your UserID/Password ?  


Look
      Ups



UltraSound - Technology Information Portal
Member of SoftWays' Medical Imaging Group - MR-TIP • Radiology-TIP • US-TIP • The-Medical-Market
Copyright © 2006 - 2016 SoftWays. All rights reserved.
Terms of Use | Privacy Policy | Advertising
 [last update: 2015-03-04 09:17:02]