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MRI Forum: CE MRA of the Liver
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bob mitchell

Sun. 5 Dec.04,
20:54
CE MRA of the Liver
Which injection rate and amount of Gadolinium works best for CE MRA of the liver with a good portal venous contrast? We have a power injector and a 1.5 T system. With a flow rate of 3 ml/sec and 20 ml contrast agent the arterial contrast but the portal phase could be better. Our MRA's are done with 15 sec. scan time for one breath hold.
lily lily

Wed. 8 Dec.04,
23:23
 Dear bob mitchell:
The injction rate and amount of C.M. of liver MRA on our experience, that are the same yours. And that can got the very will artery phase around 15sec(using smart prep. to track or fluoro-trigger to mointor and catch the C.M. arrival time ) after injection C.M. Another item about the portal vein you can settle multi-phase on option menu. After artery phase then take rest to breath and BH again(about 3-5sec) then do the second phase(portal vein phase).
you can try the way.
ps: you can try to performance it combinate ASSET, it will reduction the scan time and improve the tempory resoultion.
Tomas Randell

Thu. 16 Dec.04,
05:03
 Like lily lily we use a muliphase MRA with 3 phases (artery, portal vein and late phase).
We use an amount of 30 ml Gadolinium with an injection rate of 5 ml/sec. With this high flow rate, you get a more concentrated bolus and therefore a higher contrast for the second phase. We use CENTRA k-space acquisition and reduce the scan time with SENSE (a parallel imaging technique like ASSET ), this will help for a better timing.
Emil Cohen

Sat. 19 Mar.05,
01:03
 The above statements are correct, also remember that the portal vein is brightest in the first pass of contrast through it so having a short sequence for the arterial phase <20 seconds and going straight into the portal phase is important(ie one inspiration/expiration only between repeating the sequence). The portal vein will become brightest within 30 seconds of the artery.
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