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 'Ultrasmall Superparamagnetic Iron Oxide' 
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Result : Searchterm 'Ultrasmall Superparamagnetic Iron Oxide' found in 1 term [] and 16 definitions []
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Tumor Specific AgentsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Tumor specific MRI contrast agents are in development to provide better delineation and progression information for various tumors. Clinical oncology has a need for contrast agents that can identify tumors and metastases at a size of 100,000 cells rather than 1,000,000,000 cells. This level of sensitivity requires excellent tumor targeting of imaging agents and a high MRI signal.
Tumor specific agents accumulate at pathological tissues by passive or active targeting mechanisms. Passive targeting agents use e.g., the natural defense mechanisms in which phagocytic cells remove foreign particles from the body. Active targeting is based on a ligand-directed, site-specific accumulation of contrast agents. The availability of macromolecular contrast agents such as feruglose and ultrasmall superparamagnetic iron oxide (USPIO), which permit the assessment of tissue permeability, may also improve the detection of tumor grade, tumor type, and response to drugs that target angiogenesis.
See also Monoclonal Antibodies, Metalloporphyrins, Nitroxides and Ferrioxamine.
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Further Reading:
  News & More:
Smart Drug Developed to Show, Treat Cancer
Sunday, 18 November 2007   by www.koreatimes.co.kr    
MIT: Remote-control nanoparticles deliver drugs directly into tumors
Friday, 16 November 2007   by www.eurekalert.org    
MRI Resources 
Education - Anatomy - Artifacts - Stimulator pool - Lung Imaging - IR
 
Very Small Superparamagnetic Iron Oxide ParticlesInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
(VSOP) A new class of contrast agents with smaller particle size than SPIO or USPIO with advantages for MR angiography, caused through a longer plasma half-life.
See also Ultrasmall Superparamagnetic Iron Oxide and Superparamagnetic Iron Oxide.
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