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Result : Searchterm 'T2*' found in 2 terms [] and 41 definitions []
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Gradient Echo Multi SliceInfoSheet: - Sequences - 
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(GEMS) This pulse sequence uses a changeable flip angle instead of a 90° pulse and a gradient instead of a RF pulse to rephase the FID.
T2*, T1 weighted and proton density images can be acquired. The flip angle in combination with the TR determines the T1 weighting and the TE controls the amount of dephasing. To minimize T2* the echo time should be short.

See also Gradient Echo Sequence.
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Gradient Recalled Acquisition in Steady StateInfoSheet: - Sequences - 
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(GRASS) This sequence is very similar to FLASH, except that the spoiler pulse is eliminated. As a result, any transverse magnetization still present at the time of the next RF pulse is incorporated into the steady state. GRASS uses a RF pulse that alternates in sign. Because there is still some remaining transverse magnetization at the time of the RF pulse, a RF pulse of a degree flips the spins less than a degree from the longitudinal axis. With small flip angles, very little longitudinal magnetization is lost and the image contrast becomes almost independent of T1. Using a very short TE eliminates T2* effects, so that the images become proton density weighted. As the flip angle is increased, the contrast becomes increasingly dependent on T1 and T2*. It is in the domain of large flip angles and short TR that GRASS exhibits vastly different contrast to FLASH type sequences.
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Multi Echo Data Image CombinationInfoSheet: - Sequences - 
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(MEDIC) MEDIC is a heavily T2* weighted spoiled gradient echo sequence with multiple echoes. MEDIC uses a series of identically phase encoded gradient echoes, sampled per line in k-space. Unipolar frequency encoding gradients are used to achieve flow compensation and to avoid off resonance effects. For each echo the magnitude images are reconstructed and postprocessed by using a sum of squares algorithm to improve the signal to noise ratio. The increased receiver bandwidth reduces the T2* effects and impairment of the spatial resolution.
The multi echo data image combination sequence is potentially useful in imaging of cartilage in joints.
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T2 Star
 
(T2* or T two star) The observed time constant of the FID due to loss of phase coherence among spins oriented at an angle to the static magnetic field. Commonly due to a combination of magnetic field inhomogeneities, dB, and spin spin transverse relaxation, with the result of rapid loss in transverse magnetization and MRI signal. MRI signals can usually still be recovered as a spin echo in times less than or on the order of T2.
1/T2 * @ 1/T2 + Dw/2; Dw = gDB. The FID will generally not be exponential, so that T2* will not be unique.
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Further Reading:
  News & More:
Scientists create imaging 'toolkit' to help identify new brain tumor drug targets
Tuesday, 2 February 2016   by www.eurekalert.org    
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Abdoscan®InfoSheet: - Contrast Agents - 
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This superparamagnetic oral contrast agent consists of large iron oxide particles, coated with insoluble material. Abdoscan® particles have a mean diameter no less than 300 nm. Gastrointestinal superparamagnetic contrast agents are used for negative bowel enhancement.

Abdoscan® was approved in Europe but was taken off the market in 2000, and all sales stopped by the end of 2002.
Drug Information and Specification
NAME OF COMPOUND
DEVELOPER
CENTRAL MOIETY
Fe2+/Fe3+
CONTRAST EFFECT
T2*, predominantly negative enhancement
PHARMACOKINETIC
Gastrointestinal
CONCENTRATION
23.4 Fe/200ml
PREPARATION
Dissolve
INDICATION
Bowel marking
DEVELOPMENT STAGE
Not FDA approved
PRESENTATION
Bags with powder
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
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