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Result : Searchterm 'Relaxivity' found in 1 term [] and 50 definitions []
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Gd-DTPA-PEGInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Gd-DTPA-PEG, generic name: Gd-DTPA-PEG polymers, chemical compound: Gadolinium DTPA polyethylene glycol, central moiety: Gd2+, relaxivity: r1=6.0, B0=1.0 T
A substance under development (preclin.) as an intravascular MRI contrast agent for MR angiography and capillary permeability detection.
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Gd-DTPA-PolylysineInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: PLLGd-DTPA, generic name: (Gd-DTPA)n-polylysine, chemical compound: Gd-DTPA poly(L-lysine-Gd-diethylenetriamine-N,N,N',N'',N''-pentaacetic acid), central moiety: Gd2+, relaxivity: r1=13.1, B0=0.23T
A polymeric MRI contrast agent under development (preclin., Bayer Schering Pharma AG, Berlin, Germany) with advantages in both MRA and in the differential diagnosis of tumors, particularly in perfusion studies of the myocardium and potential in MR lung perfusion. Dozens of the relatively small molecule Gd-DTPA is bound covalently to polylysine, a large molecular weight backbone. The stable, highly water-soluble agent does not diffuse through the endothelium of the vascular system; it is subject to renal elimination.
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Imagent GIInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Perflubron® is a perfluorochemical for use as an oral contrast agent. Due to its insolubility in water it does not mix with intestinal secretions; thus bowel lumina appear homogeneously dark on MR images when Perflubron® replaces bowel contents. Filled bowel loops appear black with all pulse sequences because the contrast agent lacks mobile protons.
It is commercially available as Imagent GI. Because rapid transit through the gastrointestinal tract it reaches the rectum within 30 to 40 minutes in most patients. MR imaging of the upper abdominal region should begin within 15 minutes and of the pelvic region 15 to 60 minutes after ingestion of perflubron.

See also Classifications, Characteristics, etc.
Drug Information and Specification
NAME OF COMPOUND
Perfluoroctylbromide
DEVELOPER
CONTRAST EFFECT
Negative enhancement
Proton density reduction, signal void
PHARMACOKINETIC
Gastrointestinal
CONCENTRATION
Water immiscible liquid
DOSAGE
9 mL per kg of body weight
PREPARATION
Finished product
INDICATION
Bowel marking
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
PRESENTATION
Bottle of 200cc
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
USA
Imagent GI®
For sale
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Further Reading:
  News & More:
Slumping MRI market prompts Alliance to halt GI contrast agent effort
Wednesday, 28 September 1994   by www.searchmedica.com    
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Ln-PK-11195InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Molecular imaging agents may be useful in bimodal imaging - fluorescence and MRI. Bimodal imaging of PBR expressing cells has been possible with Ln-PK-11195, a new imaging agent for the further study of mitochondrial function and its relationship to cancer cell proliferation. By preparing cocktails of both the Gd3+ and Eu3+ or Tb3+ complexes, it will be possible to obtain non-invasive anatomic-scale images by MRI and perform microscopic-scale imaging by fluorescence on the same cell or tissue.
New agents will be created, these include a long circulating bimetallic with enhanced relaxivity for MRI. In-vitro and in-vivo studies will show the safety and efficacy of these molecular imaging agents.
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LumenHance®InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Oral administration of this liposomal encapsulated manganese chloride results in a reduction of the T1 relaxation time causing enhanced signal on T1 weighted MR images. Bracco received marketing approval in December 1997 in the United States, but marketing state is still uncertain.

See also Classifications, Characteristics, etc.
Drug Information and Specification
NAME OF COMPOUND
MnCl2, Manganese chloride tetrahydrate
CENTRAL MOIETY
Mn2+
CONTRAST EFFECT
T1, Predominantly positive enhancement
Paramagnetic
PHARMACOKINETIC
Gastrointestinal
PREPARATION
Powder for reconstitution
INDICATION
Bowel marking
DEVELOPMENT STAGE
For sale
DISTRIBUTOR
See below
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
LumenHance®
for sale
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