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Nuclear Magnetic Resonance Signal
 
The electromagnetic signal in the radio-frequency range produced by the precession of the transverse magnetization of the spins. The rotation of the transverse magnetization induces a voltage in a receiving antenna (coil), which is amplified and demodulated by the receiver circuits. Electromagnetic signal in the radio frequency range produced by the precession of the transverse magnetization of the spins. The rotation of the transverse magnetization induces a voltage in a coil, which is amplified and demodulated by the receiver;; the signal may refer only to this induced voltage.
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Further Reading:
  Basics:
Spin echoes, CPMG and T2 relaxation - Introductory NMR & MRI from Magritek
2013   by www.azom.com    
NMR Spectroscopy - Theory
   by www.shu.ac.uk    
  News & More:
A powder to enhance NMR signals
Thursday, 12 December 2013   by phys.org    
MRI Resources 
MRI Physics - Libraries - Corporations - Breast MRI - Distributors - Health
 
DeviceForum -
related threadsInfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.
 
Magnetic resonance imaging (MRI) is based on the magnetic resonance phenomenon, and is used for medical diagnostic imaging since ca. 1977 (see also MRI History).
The first developed MRI devices were constructed as long narrow tunnels. In the meantime the magnets became shorter and wider. In addition to this short bore magnet design, open MRI machines were created. MRI machines with open design have commonly either horizontal or vertical opposite installed magnets and obtain more space and air around the patient during the MRI test.
The basic hardware components of all MRI systems are the magnet, producing a stable and very intense magnetic field, the gradient coils, creating a variable field and radio frequency (RF) coils which are used to transmit energy and to encode spatial positioning. A computer controls the MRI scanning operation and processes the information.
The range of used field strengths for medical imaging is from 0.15 to 3 T. The open MRI magnets have usually field strength in the range 0.2 Tesla to 0.35 Tesla. The higher field MRI devices are commonly solenoid with short bore superconducting magnets, which provide homogeneous fields of high stability.
There are this different types of magnets:
The majority of superconductive magnets are based on niobium-titanium (NbTi) alloys, which are very reliable and require extremely uniform fields and extreme stability over time, but require a liquid helium cryogenic system to keep the conductors at approximately 4.2 Kelvin (-268.8° Celsius). To maintain this temperature the magnet is enclosed and cooled by a cryogen containing liquid helium (sometimes also nitrogen).
The gradient coils are required to produce a linear variation in field along one direction, and to have high efficiency, low inductance and low resistance, in order to minimize the current requirements and heat deposition. A Maxwell coil usually produces linear variation in field along the z-axis; in the other two axes it is best done using a saddle coil, such as the Golay coil.
The radio frequency coils used to excite the nuclei fall into two main categories; surface coils and volume coils. The essential element for spatial encoding, the gradient coil sub-system of the MRI scanner is responsible for the encoding of specialized contrast such as flow information, diffusion information, and modulation of magnetization for spatial tagging.
An analog to digital converter turns the nuclear magnetic resonance signal to a digital signal. The digital signal is then sent to an image processor for Fourier transformation and the image of the MRI scan is displayed on a monitor.

For Ultrasound Imaging (USI) see Ultrasound Machine at Medical-Ultrasound-Imaging.com.

See also the related poll results: 'In 2010 your scanner will probably work with a field strength of' and 'Most outages of your scanning system are caused by failure of'
Radiology-tip.comradGamma Camera,  Linear Accelerator
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Further Reading:
  News & More:
small-steps-can-yield-big-energy-savings-and-cut-emissions-mris
Thursday, 27 April 2023   by www.itnonline.com    
Portable MRI can detect brain abnormalities at bedside
Tuesday, 8 September 2020   by news.yale.edu    
Point-of-Care MRI Secures FDA 510(k) Clearance
Thursday, 30 April 2020   by www.diagnosticimaging.com    
World's First Portable MRI Cleared by FDA
Monday, 17 February 2020   by www.medgadget.com    
Low Power MRI Helps Image Lungs, Brings Costs Down
Thursday, 10 October 2019   by www.medgadget.com    
Cheap, portable scanners could transform brain imaging. But how will scientists deliver the data?
Tuesday, 16 April 2019   by www.sciencemag.org    
The world's strongest MRI machines are pushing human imaging to new limits
Wednesday, 31 October 2018   by www.nature.com    
Kyoto University and Canon reduce cost of MRI scanner to one tenth
Monday, 11 January 2016   by www.electronicsweekly.com    
A transportable MRI machine to speed up the diagnosis and treatment of stroke patients
Wednesday, 22 April 2015   by medicalxpress.com    
Portable 'battlefield MRI' comes out of the lab
Thursday, 30 April 2015   by physicsworld.com    
Chemists develop MRI technique for peeking inside battery-like devices
Friday, 1 August 2014   by www.eurekalert.org    
New devices doubles down to detect and map brain signals
Monday, 23 July 2012   by scienceblog.com    
MRI Resources 
Distributors - Absorption and Emission - Diffusion Weighted Imaging - Societies - Pacemaker - Contrast Agents
 
MRI History
 
Sir Joseph Larmor (1857-1942) developed the equation that the angular frequency of precession of the nuclear spins being proportional to the strength of the magnetic field. [Larmor relationship]
In the 1930's, Isidor Isaac Rabi (Columbia University) succeeded in detecting and measuring single states of rotation of atoms and molecules, and in determining the mechanical and magnetic moments of the nuclei.
Felix Bloch (Stanford University) and Edward Purcell (Harvard University) developed instruments, which could measure the magnetic resonance in bulk material such as liquids and solids. (Both honored with the Nobel Prize for Physics in 1952.) [The birth of the NMR spectroscopy]
In the early 70's, Raymond Damadian (State University of New York) demonstrated with his NMR device, that there are different T1 relaxation times between normal and abnormal tissues of the same type, as well as between different types of normal tissues.
In 1973, Paul Lauterbur (State University of New York) described a new imaging technique that he termed Zeugmatography. By utilizing gradients in the magnetic field, this technique was able to produce a two-dimensional image (back-projection). (Through analysis of the characteristics of the emitted radio waves, their origin could be determined.) Peter Mansfield further developed the utilization of gradients in the magnetic field and the mathematically analysis of these signals for a more useful imaging technique. (Paul C Lauterbur and Peter Mansfield were awarded with the 2003 Nobel Prize in Medicine.)
In 1975, Richard Ernst introduced 2D NMR using phase and frequency encoding, and the Fourier Transform. Instead of Paul Lauterbur's back-projection, he timely switched magnetic field gradients ('NMR Fourier Zeugmatography'). [This basic reconstruction method is the basis of current MRI techniques.]
1977/78: First images could be presented. A cross section through a finger by Peter Mansfield and Andrew A. Maudsley. Peter Mansfield also could present the first image through the abdomen.
In 1977, Raymond Damadian completed (after 7 years) the first MR scanner (Indomitable). In 1978, he founded the FONAR Corporation, which manufactured the first commercial MRI scanner in 1980. Fonar went public in 1981.
1981: Schering submitted a patent application for Gd-DTPA dimeglumine.
1982: The first 'magnetization-transfer' imaging by Robert N. Muller.
In 1983, Toshiba obtained approval from the Ministry of Health and Welfare in Japan for the first commercial MRI system.
In 1984, FONAR Corporation receives FDA approval for its first MRI scanner.
1986: Jürgen Hennig, A. Nauerth, and Hartmut Friedburg (University of Freiburg) introduced RARE (rapid acquisition with relaxation enhancement) imaging. Axel Haase, Jens Frahm, Dieter Matthaei, Wolfgang Haenicke, and Dietmar K. Merboldt (Max-Planck-Institute, Göttingen) developed the FLASH (fast low angle shot) sequence.
1988: Schering's MAGNEVIST gets its first approval by the FDA.
In 1991, fMRI was developed independently by the University of Minnesota's Center for Magnetic Resonance Research (CMRR) and Massachusetts General Hospital's (MGH) MR Center.
From 1992 to 1997 Fonar was paid for the infringement of it's patents from 'nearly every one of its competitors in the MRI industry including giant multi-nationals as Toshiba, Siemens, Shimadzu, Philips and GE'.
 
Images, Movies, Sliders:
 Cardiac Infarct Short Axis Cine Overview  Open this link in a new window
    

Courtesy of  Robert R. Edelman
 
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Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
Fonar Our History
   by www.fonar.com    
  News & More:
Scientists win Nobels for work on MRI
Tuesday, 10 June 2003   by usatoday30.usatoday.com    
2001 Lemelson-MIT Lifetime Achievement Award Winner
   by web.mit.edu    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
Searchterm 'Nuclear Magnetic Resonance Signal' was also found in the following service: 
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Magnetic Resonance
 
(MR) Resonance phenomenon resulting in the absorption and/or emission of electromagnetic energy by nuclei (for that reason also nuclear magnetic resonance) or electrons in a static magnetic field, after excitation by a suitable RF magnetic field.
The peak resonance frequency is proportional to the magnetic field, and is given by the Larmor equation. Only unpaired electrons or nuclei with a spin exhibit magnetic resonance. The absorption or emission of energy by atomic nuclei in an external magnetic field after the application of RF excitation pulses using frequencies, which satisfy the conditions of the Larmor equation.
The magnetic resonance phenomenon may be used in one of these ways:
By manipulation of the external field (application of gradient fields), the resonance frequency can become dependent on spatial location, and hence images may be generated (MRI).
The effect of the electron cloud in any atom or molecule is to slightly shield the nucleus from the external field, thus giving any chemical species a characteristic frequency. This gives rise to 'spectra' where nuclei in a molecule give rise to specific signals, thus facilitating the detection of individual chemicals by means of their frequency spectra (MRS)
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• View the NEWS results for 'Magnetic Resonance' (259).Open this link in a new window.
 
Further Reading:
  Basics:
Magnetic Resonance Imaging, History & Introduction
2000   by www.cis.rit.edu    
  News & More:
The 2003 Nobel Prize in Physiology or Medicine
2003   by www.nobel.se    
MRI Resources 
Crystallography - MRI Technician and Technologist Career - Knee MRI - Raman Spectroscopy - MRI Accidents - Distributors
 
Magnetic Resonance Imaging MRI
 
(MRI) Magnetic resonance imaging is a noninvasive medical imaging technique that uses the interaction between radio frequency pulses, a strong magnetic field and body tissue to obtain images of slices/planes from inside the body. These magnets generate fields from approx. 2000 times up to 30000 times stronger than that of the Earth. The use of nuclear magnetic resonance principles produces extremely detailed pictures of the body tissue without the need for x-ray exposure and gives diagnostic information of various organs.
Measured are mobile hydrogen nuclei (protons are the hydrogen atoms of water, the 'H' in H20), the majority of elements in the body. Only a small part of them contribute to the measured signal, caused by their different alignment in the magnetic field. Protons are capable of absorbing energy if exposed to short radio wave pulses (electromagnetic energy) at their resonance frequency. After the absorption of this energy, the nuclei release this energy so that they return to their initial state of equilibrium.
This transmission of energy by the nuclei as they return to their initial state is what is observed as the MRI signal. The subtle differing characteristic of that signal from different tissues combined with complex mathematical formulas analyzed on modern computers is what enables MRI imaging to distinguish between various organs. Any imaging plane, or slice, can be projected, and then stored or printed.
The measured signal intensity depends jointly on the spin density and the relaxation times (T1 time and T2 time), with their relative importance depending on the particular imaging technique and choice of interpulse times. Any motion such as blood flow, respiration, etc. also affects the image brightness.
Magnetic resonance imaging is particularly sensitive in assessing anatomical structures, organs and soft tissues for the detection and diagnosis of a broad range of pathological conditions. MRI pictures can provide contrast between benign and pathological tissues and may be used to stage cancers as well as to evaluate the response to treatment of malignancies. The need for biopsy or exploratory surgery can be eliminated in some cases, and can result in earlier diagnosis of many diseases.

See also MRI History and Functional Magnetic Resonance Imaging (fMRI).
 
Images, Movies, Sliders:
 CE-MRA of the Carotid Arteries Colored MIP  Open this link in a new window
    
SlidersSliders Overview

 Anatomic Imaging of the Lumbar Spine  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Normal Dual Inversion Fast Spin-echo  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Breast MRI Images T2 And T1 Pre - Post Contrast  Open this link in a new window
 Anatomic Imaging of the Shoulder  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 
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Further Reading:
  Basics:
Bringing More Value to Imaging Departments With MRI
Friday, 4 October 2019   by www.itnonline.com    
A Short History of the Magnetic Resonance Imaging (MRI)
   by www.teslasociety.com    
On the Horizon - Next Generation MRI
Wednesday, 23 October 2013   by thefutureofthings.com    
MRI's inside story
Thursday, 4 December 2003   by www.economist.com    
  News & More:
High-resolution MRI enables direct imaging of neuronal activity - DIANA – direct imaging of neuronal activity
Friday, 18 November 2022   by physicsworld.com    
New MRI technique can 'see' molecular changes in the brain
Thursday, 5 September 2019   by medicalxpress.com    
How new MRI technology is transforming the patient experience
Tuesday, 14 May 2019   by newsroom.gehealthcare.com    
Metamaterials boost sensitivity of MRI machines
Thursday, 14 January 2016   by www.eurekalert.org    
MRI technique allows study of wrist in motion
Monday, 6 January 2014   by www.healthimaging.com    
New imaging technology promising for several types of cancer
Thursday, 29 August 2013   by medicalxpress.com    
MRI method for measuring MS progression validated
Thursday, 19 December 2013   by www.eurekalert.org    
MRI Resources 
Software - Mobile MRI Rental - PACS - Mass Spectrometry - Cardiovascular Imaging - NMR
 
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