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Magnetic Field Mapping
 
The mapping of the magnetic field by measuring or imaging the spatial distribution of magnetic field strength, can be performed by scanning with a probe and handles a large range of field strengths, but is slow and tedious. Accurate field maps can be made by measuring the Larmor frequency as a function of position.
The field must be homogeneous enough to allow MR imaging to be performed, than the magnetic field can be mapped by different methods.
1. The adaptation of chemical shift imaging.
2. The faster one measures the change in signal phase in an image obtained with a gradient echo pulse sequence resulting from a change in echo time TE, which is proportional to the local field strength.
Also useful is a spin echo pulse sequence with data collection from two time locations of the readout gradient and the data acquisition interval, where each having a known shift of the acquisition center away from the spin echo.
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Further Reading:
  News & More:
sPHENIX assembly update: magnet mapped, detectors prepared
Friday, 23 December 2022   by www.eurekalert.org    
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Diffusion Weighted ImagingForum -
related threadsMRI Resource Directory:
 - Diffusion Weighted Imaging -
 
(DWI) Magnetic resonance imaging is sensitive to diffusion, because the diffusion of water molecules along a field gradient reduces the MR signal. In areas of lower diffusion the signal loss is less intense and the display from this areas is brighter. The use of a bipolar gradient pulse and suitable pulse sequences permits the acquisition of diffusion weighted images (images in which areas of rapid proton diffusion can be distinguished from areas with slow diffusion).
Based on echo planar imaging, multislice DWI is today a standard for imaging brain infarction. With enhanced gradients, the whole brain can be scanned within seconds. The degree of diffusion weighting correlates with the strength of the diffusion gradients, characterized by the b-value, which is a function of the gradient related parameters: strength, duration, and the period between diffusion gradients.
Certain illnesses show restrictions of diffusion, for example demyelinization and cytotoxic edema. Areas of cerebral infarction have decreased apparent diffusion, which results in increased signal intensity on diffusion weighted MRI scans. DWI has been demonstrated to be more sensitive for the early detection of stroke than standard pulse sequences and is closely related to temperature mapping.
DWIBS is a new diffusion weighted imaging technique for the whole body that produces PET-like images. The DWIBS sequence has been developed with the aim to detect lymph nodes and to differentiate normal and hyperplastic from metastatic lymph nodes. This may be possible caused by alterations in microcirculation and water diffusivity within cancer metastases in lymph nodes.

See also Diffusion Weighted Sequence, Perfusion Imaging, ADC Map, Apparent Diffusion Coefficient, and Diffusion Tensor Imaging.
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• View the DATABASE results for 'Diffusion Weighted Imaging' (11).Open this link in a new window


• View the NEWS results for 'Diffusion Weighted Imaging' (4).Open this link in a new window.
 
Further Reading:
  Basics:
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
Novel MRI Technique Could Reduce Breast Biopsies, University of Washington Study
Tuesday, 2 October 2012   by www.eurekalert.org    
Quantitative Apparent Diffusion Coefficient Measurements Obtained by 3-Tesla MRI Are Correlated with Biomarkers of Bladder Cancer Proliferative Activity
   by www.plosone.org    
  News & More:
Stability and repeatability of diffusion-weighted imaging (DWI) of normal pancreas on 5.0 Tesla magnetic resonance imaging (MRI)
Monday, 24 July 2023   by www.nature.com    
MRI innovation makes cancerous tissue light up and easier to see
Monday, 21 March 2022   by www.sciencedaily.com    
Diffusion MRI and machine learning models classify childhood brain tumours
Saturday, 6 March 2021   by physicsworld.com    
Diffusion-weighted MRI in Advanced Epithelial Ovarian Cancer: Apparent Diffusion Coefficient as a Response Marker
Tuesday, 1 October 2019   by pubs.rsna.org    
Novel Imaging Technique Improves Prostate Cancer Detection
Tuesday, 6 January 2015   by health.ucsd.edu    
High-b-value Diffusion-weighted MR Imaging of Suspected Brain Infarction
2000   by www.ajnr.org    
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Magnetic Source ImagingInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.MRI Resource Directory:
 - Functional MRI -
 
(MSI) The combination of biomagnetic field detection and MR imaging into a merged data set. Most applications of MSI involve the combined use of MRI and measurement of magnetic fields created by electric currents in the brain, so-called magnetoencephalography MEG.
MEG allows calculation of the source of the measured biomagnetic fields, and thereby localization of many regional brain functions, such as mapping of the sensorimotor, auditory and visual cortex and also localization of epileptogenic foci. The MEG coordinate system is defined by anatomical landmarks, which are easily identified also with MRI, making it possible to align the 3D MEG data with the 3D MR image data. The resulting magnetic source images show the spatial relationships between the functional area provided by MEG and the neighboring anatomy and pathology, both provided by MRI.
Cardiac applications of MSI are also being explored. The electric currents in the myocardium create extrathoracic magnetic fields and the source of these fields may be calculated by the same principles as those used in MEG. Possible cardiac applications include mapping of arrhythmogenic sites prior to ablation therapy.
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• View the DATABASE results for 'Magnetic Source Imaging' (2).Open this link in a new window


• View the NEWS results for 'Magnetic Source Imaging' (2).Open this link in a new window.
 
Further Reading:
  News & More:
iMPI: An Exploration of Post-Launch Advancements
Friday, 29 September 2023   by www.diagnosticimaging.com    
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Perfusion ImagingForum -
related threadsInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(PWI - Perfusion Weighted Imaging) Perfusion MRI techniques (e.g. PRESTO - Principles of Echo Shifting using a Train of Observations) are sensitive to microscopic levels of blood flow. Contrast enhanced relative cerebral blood volume (rCBV) is the most used perfusion imaging. Both, the ready availability and the T2* susceptibility effects of gadolinium, rather than the T1 shortening effects make gadolinium a suitable agent for use in perfusion imaging. Susceptibility here refers to the loss of MR signal, most marked on T2* (gradient echo)-weighted and T2 (spin echo)-weighted sequences, caused by the magnetic field-distorting effects of paramagnetic substances.
T2* perfusion uses dynamic sequences based on multi or single shot techniques. The T2* (T2) MRI signal drop within or across a brain region is caused by spin dephasing during the rapid passage of contrast agent through the capillary bed. The signal decrease is used to compute the relative perfusion to that region. The bolus through the tissue is only a few seconds, high temporal resolution imaging is required to obtain sequential images during the wash in and wash out of the contrast material and therefore, resolve the first pass of the tracer. Due to the high temporal resolution, processing and calculation of hemodynamic maps are available (including mean transit time (MTT), time to peak (TTP), time of arrival (T0), negative integral (N1) and index.
An important neuroradiological indication for MRI is the evaluation of incipient or acute stroke via perfusion and diffusion imaging. Diffusion imaging can demonstrate the central effect of a stroke on the brain, whereas perfusion imaging visualizes the larger 'second ring' delineating blood flow and blood volume. Qualitative and in some instances quantitative (e.g. quantitative imaging of perfusion using a single subtraction) maps of regional organ perfusion can thus be obtained.
Echo planar and potentially echo volume techniques together with appropriate computing power offer real time images of dynamic variations in water characteristics reflecting perfusion, diffusion, oxygenation (see also Oxygen Mapping) and flow.
Another type of perfusion MR imaging allows the evaluation of myocardial ischemia during pharmacologic stress. After e.g., adenosine infusion, multiple short axis views (see cardiac axes) of the heart are obtained during the administration of gadolinium contrast. Ischemic areas show up as areas of delayed and diminished enhancement. The MRI stress perfusion has been shown to be more accurate than nuclear SPECT exams. Myocardial late enhancement and stress perfusion imaging can also be performed during the same cardiac MRI examination.
 
Images, Movies, Sliders:
 Normal Lung Gd Perfusion MRI  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 Left Circumflex Ischemia First-pass Contrast Enhancement  Open this link in a new window
 
Radiology-tip.comradPerfusion Scintigraphy
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Medical-Ultrasound-Imaging.comBolus Injection
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• View the DATABASE results for 'Perfusion Imaging' (16).Open this link in a new window


• View the NEWS results for 'Perfusion Imaging' (3).Open this link in a new window.
 
Further Reading:
  Basics:
CHAPTER 55: Ischemia
2003
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
  News & More:
Non-invasive diagnostic procedures for suspected CHD: Search reveals informative evidence
Wednesday, 8 July 2020   by medicalxpress.co    
Implementation of Dual-Source RF Excitation in 3 T MR-Scanners Allows for Nearly Identical ADC Values Compared to 1.5 T MR Scanners in the Abdomen
Wednesday, 29 February 2012   by www.plosone.org    
Motion-compensation of Cardiac Perfusion MRI using a Statistical Texture Ensemble(.pdf)
June 2003   by www.imm.dtu.dk    
Turbo-FLASH Based Arterial Spin Labeled Perfusion MRI at 7 T
Thursday, 20 June 2013   by www.plosone.org    
Measuring Cerebral Blood Flow Using Magnetic Resonance Imaging Techniques
1999   by www.stanford.edu    
Vascular Filters of Functional MRI: Spatial Localization Using BOLD and CBV Contrast
MRI Resources 
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Echo Offset
 
Echo offset is the time setting of spin echo and gradient echo to be not coincident and to generate phase differences between different spectral line signals (e.g., water and fat). The echo offset is the product of the frequency line difference and the time difference (TD) in the echo times and is equal to the magnitude of the result of the phase difference between two spectral lines. Phases may not change linearly with echo offset time in the presence of a large field inhomogeneity. An echo offset excitation pulse sequence can be used in the magnetic field mapping method, to generate maps from which the standard deviation of the phase difference can be calculated.
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Further Reading:
  News & More:
T1rho-prepared balanced gradient echo for rapid 3D T1rho MRI
Monday, 1 September 2008   by www.ncbi.nlm.nih.gov    
A short-TR single-echo spin-echo breath-hold method for assessing liver T2
Sunday, 10 December 2023   by link.springer.com    
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