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Low Angle Spin EchoInfoSheet: - Sequences - 
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Gradient Echo SequenceForum -
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Gradient Echo Sequence Timing Diagram (GRE - sequence) A gradient echo is generated by using a pair of bipolar gradient pulses. In the pulse sequence timing diagram, the basic gradient echo sequence is illustrated. There is no refocusing 180° pulse and the data are sampled during a gradient echo, which is achieved by dephasing the spins with a negatively pulsed gradient before they are rephased by an opposite gradient with opposite polarity to generate the echo.
See also the Pulse Sequence Timing Diagram. There you will find a description of the components.
The excitation pulse is termed the alpha pulse α. It tilts the magnetization by a flip angle α, which is typically between 0° and 90°. With a small flip angle there is a reduction in the value of transverse magnetization that will affect subsequent RF pulses. The flip angle can also be slowly increased during data acquisition (variable flip angle: tilt optimized nonsaturation excitation). The data are not acquired in a steady state, where z-magnetization recovery and destruction by ad-pulses are balanced. However, the z-magnetization is used up by tilting a little more of the remaining z-magnetization into the xy-plane for each acquired imaging line.
Gradient echo imaging is typically accomplished by examining the FID, whereas the read gradient is turned on for localization of the signal in the readout direction. T2* is the characteristic decay time constant associated with the FID. The contrast and signal generated by a gradient echo depend on the size of the longitudinal magnetization and the flip angle. When α = 90° the sequence is identical to the so-called partial saturation or saturation recovery pulse sequence. In standard GRE imaging, this basic pulse sequence is repeated as many times as image lines have to be acquired. Additional gradients or radio frequency pulses are introduced with the aim to spoil to refocus the xy-magnetization at the moment when the spin system is subject to the next α pulse.
As a result of the short repetition time, the z-magnetization cannot fully recover and after a few initial α pulses there is an equilibrium established between z-magnetization recovery and z-magnetization reduction due to the α pulses.
Gradient echoes have a lower SAR, are more sensitive to field inhomogeneities and have a reduced crosstalk, so that a small or no slice gap can be used. In or out of phase imaging depending on the selected TE (and field strength of the magnet) is possible. As the flip angle is decreased, T1 weighting can be maintained by reducing the TR. T2* weighting can be minimized by keeping the TE as short as possible, but pure T2 weighting is not possible. By using a reduced flip angle, some of the magnetization value remains longitudinal (less time needed to achieve full recovery) and for a certain T1 and TR, there exist one flip angle that will give the most signal, known as the "Ernst angle".
Contrast values:
PD weighted: Small flip angle (no T1), long TR (no T1) and short TE (no T2*)
T1 weighted: Large flip angle (70°), short TR (less than 50ms) and short TE
T2* weighted: Small flip angle, some longer TR (100 ms) and long TE (20 ms)

Classification of GRE sequences can be made into four categories:
See also Gradient Recalled Echo Sequence, Spoiled Gradient Echo Sequence, Refocused Gradient Echo Sequence, Ultrafast Gradient Echo Sequence.
 
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Further Reading:
  Basics:
Enhanced Fast GRadient Echo 3-Dimensional (efgre3D) or THRIVE
   by www.mri.tju.edu    
  News & More:
MRI evaluation of fatty liver in day to day practice: Quantitative and qualitative methods
Wednesday, 3 September 2014   by www.sciencedirect.com    
T1rho-prepared balanced gradient echo for rapid 3D T1rho MRI
Monday, 1 September 2008   by www.ncbi.nlm.nih.gov    
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Flip Angle
 
(FA) The flip angle a is used to define the angle of excitation for a field echo pulse sequence. It is the angle to which the net magnetization is rotated or tipped relative to the main magnetic field direction via the application of a RF excitation pulse at the Larmor frequency. It is also referred to as the tip angle, nutation angle or angle of nutation.
The radio frequency power (which is proportional to the square of the amplitude) of the pulse is proportional to a through which the spins are tilted under its influence. Flip angles between 0° and 90° are typically used in gradient echo sequences, 90° and a series of 180° pulses in spin echo sequences and an initial 180° pulse followed by a 90° and a 180° pulse in inversion recovery sequences.
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• View the NEWS results for 'Flip Angle' (1).Open this link in a new window.
 
Further Reading:
  Basics:
What MRI Sequences Produce the Highest Specific Absorption Rate (SAR), and Is There Something We Should Be Doing to Reduce the SAR During Standard Examinations?
Thursday, 16 April 2015   by www.ajronline.org    
Mapping of low flip angles in magnetic resonance(.pdf)
Saturday, 1 January 2011   by www.hal.inserm.fr    
  News & More:
A practical guideline for T1 reconstruction from various flip angles in MRI
Saturday, 1 October 2016   by journals.sagepub.com    
Clinical evaluation of a speed optimized T2 weighted fast spin echo sequence at 3.0 T using variable flip angle refocusing, half-Fourier acquisition and parallel imaging
Wednesday, 25 October 2006
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Gradient Motion Rephasing
 
(GMR) The application of strategic gradient pulses can compensate the objectionable spin phase effects of flow motion. That means the reducing of flow effects, e.g. gradient moment nulling of the first order of flow. The simplest velocity-compensated pulse sequence is the symmetrical second echo of a spin echo pulse sequence.
Gradient field changes can be configured in such a way that during an echo the magnetization signal vectors for all pixels have zero phase angle independent of velocities, accelerations etc. of the measured tissue. E.g. the adjustment to zero at the time TE of the net moments of the amplitude of the waveform of the magnetic field gradients with time. The zeroth moment is the area under the curve, the first moment is the 'center of gravity' etc. The aim is to minimize the phase shifts acquired by the transverse magnetization of excited nuclei moving along the gradients (including the effect of refocusing RF pulses), particularly for the reduction of image artifacts due to motion.
Also called Flow Compensation (FC), Motion Artifact Suppression Technique (MAST), Flow motion compression (STILL), Gradient Rephasing (GR), Shimadzu Motion Artifact Reduction Technique (SMART).
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Further Reading:
  Basics:
Motion Compensation in MR Imaging
   by ccn.ucla.edu    
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Steady State Free PrecessionInfoSheet: - Sequences - 
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(SFP or SSFP) Steady state free precession is any field or gradient echo sequence in which a non-zero steady state develops for both components of magnetization (transverse and longitudinal) and also a condition where the TR is shorter than the T1 and T2 times of the tissue. If the RF pulses are close enough together, the MR signal will never completely decay, implying that the spins in the transverse plane never completely dephase. The flip angle and the TR maintain the steady state. The flip angle should be 60-90° if the TR is 100 ms, if the TR is less than 100 ms, then the flip angle for steady state should be 45-60°.
Steady state free precession is also a method of MR excitation in which strings of RF pulses are applied rapidly and repeatedly with interpulse intervals short compared to both T1 and T2. Alternating the phases of the RF pulses by 180° can be useful. The signal reforms as an echo immediately before each RF pulse; immediately after the RF pulse there is additional signal from the FID produced by the pulse.
The strength of the FID will depend on the time between pulses (TR), the tissue and the flip angle of the pulse; the strength of the echo will additionally depend on the T2 of the tissue. With the use of appropriate dephasing gradients, the signal can be observed as a frequency-encoded gradient echo either shortly before the RF pulse or after it; the signal immediately before the RF pulse will be more highly T2 weighted. The signal immediately after the RF pulse (in a rapid series of RF pulses) will depend on T2 as well as T1, unless measures are taken to destroy signal refocusing and prevent the development of steady state free precession.
To avoid setting up a state of SSFP when using rapidly repeated excitation RF pulses, it may be necessary to spoil the phase coherence between excitations, e.g. with varying phase shifts or timing of the exciting RF pulses or varying spoiler gradient pulses between the excitations.
Steady state free precession imaging methods are quite sensitive to the resonant frequency of the material. Fluctuating equilibrium MR (see also FIESTA and DRIVE)and linear combination SSFP actually use this sensitivity for fat suppression. Fat saturated SSFP (FS-SSFP) use a more complex fat suppression scheme than FEMR or LCSSFP, but has a 40% lower scan time.
A new family of steady state free precession sequences use a balanced gradient, a gradient waveform, which will act on any stationary spin on resonance between 2 consecutive RF pulses and return it to the same phase it had before the gradients were applied.
This sequences include, e.g. Balanced Fast Field Echo - bFFE, Balanced Turbo Field Echo - bTFE, Fast Imaging with Steady Precession - TrueFISP and Balanced SARGE - BASG.

See also FIESTA.
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Further Reading:
  News & More:
Comparison of New Methods for Magnetic Resonance Imaging of Articular Cartilage(.pdf)
2002
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