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 'Gradient and Spin Echo' 
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Gradient Echo SequenceForum -
related threadsInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
Gradient Echo Sequence Timing Diagram (GRE - sequence) A gradient echo is generated by using a pair of bipolar gradient pulses. In the pulse sequence timing diagram, the basic gradient echo sequence is illustrated. There is no refocusing 180° pulse and the data are sampled during a gradient echo, which is achieved by dephasing the spins with a negatively pulsed gradient before they are rephased by an opposite gradient with opposite polarity to generate the echo.
See also the Pulse Sequence Timing Diagram. There you will find a description of the components.
The excitation pulse is termed the alpha pulse α. It tilts the magnetization by a flip angle α, which is typically between 0° and 90°. With a small flip angle there is a reduction in the value of transverse magnetization that will affect subsequent RF pulses. The flip angle can also be slowly increased during data acquisition (variable flip angle: tilt optimized nonsaturation excitation). The data are not acquired in a steady state, where z-magnetization recovery and destruction by ad-pulses are balanced. However, the z-magnetization is used up by tilting a little more of the remaining z-magnetization into the xy-plane for each acquired imaging line.
Gradient echo imaging is typically accomplished by examining the FID, whereas the read gradient is turned on for localization of the signal in the readout direction. T2* is the characteristic decay time constant associated with the FID. The contrast and signal generated by a gradient echo depend on the size of the longitudinal magnetization and the flip angle. When α = 90° the sequence is identical to the so-called partial saturation or saturation recovery pulse sequence. In standard GRE imaging, this basic pulse sequence is repeated as many times as image lines have to be acquired. Additional gradients or radio frequency pulses are introduced with the aim to spoil to refocus the xy-magnetization at the moment when the spin system is subject to the next α pulse.
As a result of the short repetition time, the z-magnetization cannot fully recover and after a few initial α pulses there is an equilibrium established between z-magnetization recovery and z-magnetization reduction due to the α pulses.
Gradient echoes have a lower SAR, are more sensitive to field inhomogeneities and have a reduced crosstalk, so that a small or no slice gap can be used. In or out of phase imaging depending on the selected TE (and field strength of the magnet) is possible. As the flip angle is decreased, T1 weighting can be maintained by reducing the TR. T2* weighting can be minimized by keeping the TE as short as possible, but pure T2 weighting is not possible. By using a reduced flip angle, some of the magnetization value remains longitudinal (less time needed to achieve full recovery) and for a certain T1 and TR, there exist one flip angle that will give the most signal, known as the "Ernst angle".
Contrast values:
PD weighted: Small flip angle (no T1), long TR (no T1) and short TE (no T2*)
T1 weighted: Large flip angle (70°), short TR (less than 50ms) and short TE
T2* weighted: Small flip angle, some longer TR (100 ms) and long TE (20 ms)

Classification of GRE sequences can be made into four categories:
See also Gradient Recalled Echo Sequence, Spoiled Gradient Echo Sequence, Refocused Gradient Echo Sequence, Ultrafast Gradient Echo Sequence.
 
Images, Movies, Sliders:
 MRI Liver In Phase  Open this link in a new window
    
 MRI Liver Out Of Phase  Open this link in a new window
    
 MVP Parasternal  Open this link in a new window
 Breast MRI Images T1 Pre - Post Contrast  Open this link in a new window
 Circle of Willis, Time of Flight, MIP  Open this link in a new window
    
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• Related Searches:
    • Steady State Free Precession
    • Abdominal Imaging
    • Contrast Enhanced MRI
    • Free Induction Decay
    • Ultrafast Gradient Echo Sequence
 
Further Reading:
  Basics:
Enhanced Fast GRadient Echo 3-Dimensional (efgre3D) or THRIVE
   by www.mri.tju.edu    
  News & More:
MRI evaluation of fatty liver in day to day practice: Quantitative and qualitative methods
Wednesday, 3 September 2014   by www.sciencedirect.com    
T1rho-prepared balanced gradient echo for rapid 3D T1rho MRI
Monday, 1 September 2008   by www.ncbi.nlm.nih.gov    
MRI Resources 
Contrast Agents - Process Analysis - General - Cochlear Implant - NMR - MRI Technician and Technologist Jobs
 
CHORUS 1.5Tâ„¢InfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.isoltech.co.kr/english/product/default.htm 'Next generation MRI system 1.5T CHORUS developed by ISOL Technology is optimized for both clinical diagnostic imaging and for research development.
CHORUS offers the complete range of feature oriented advanced imaging techniques- for both clinical routine and research. The compact short bore magnet, the patient friendly design and the gradient technology make the innovation to new degree of perfection in magnetic resonance.'
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Short bore
Head, C-spine, L-spine, TMJ, Knee, Shoulder, General purpose, Phased Array System: 4 digital receiver channels (Up to 12 channels)
Optional
SYNCHRONIZATION
ECG/peripheral: Optional/yes, respiratory gating
PULSE SEQUENCES
Spin Echo, Gradient Echo, Fast Spin Echo, Inversion Recovery (STIR, Fluid Attenuated Inversion Recovery), FLASH, FISP, PSIF, Turbo Flash ( MPRAGE ),TOF MR Angiography, Standard echo planar imaging package (SE-EPI, GE-EPI), Optional: Advanced P.A. Imaging Package (up to 4 ch.), Advanced echo planar imaging package, Single Shot and Diffusion Weighted EPI, IR/FLAIR EPI
IMAGING MODES
2D/3D, Travelling Sat, Multi-Slab 3D, MTC and TONE Pulse Sequence, Fat/Water Suppression, Presaturation (up to 6 bands), Flow Compensation using GMR pulse, Multi-Slice, Multi-Group Imaging
SINGLE/MULTI SLICE
Image reconstruction time (2562 ) : 0.02 s
FOV
40 cm
BORE DIAMETER
or W x H
58 cm diameter (patient)
MAGNET WEIGHT
4050 kg
H*W*D
233 x 206 x 160 cm
COOLING SYSTEM TYPE
Water-cooled coil and air-cooled amplifier
CRYOGEN USE
0.07 L/hr helium
STRENGTH
20 mT/m (Upto 27 mT/m)
5-GAUSS FRINGE FIELD
2.5 m / 3.8 m
Passive and active
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• View the DATABASE results for 'CHORUS 1.5T™' (2).Open this link in a new window

MRI Resources 
Mobile MRI - Stent - Breast Implant - Education - Spectroscopy pool - Pathology
 
ENCORE 0.5Tâ„¢InfoSheet: - Devices -
Intro, 
Types of Magnets, 
Overview, 
etc.MRI Resource Directory:
 - Devices -
 
www.isoltech.co.kr/english/product/05t.htm 'MRI system is not an expensive equipment anymore. ENCORE developed by ISOL Technology is a low cost MRI system with the advantages like of the 1.0T MRI scanner. Developed specially for the overseas market, the ENCORE is gaining popularity in the domestic market by medium sized hospitals.
Due to the optimum RF and Gradient application technology. ENCORE enables to obtain high resolution imaging and 2D/3D Angio images which was only possible in high field MR systems.'
- Less consumption of the helium gas due to the ultra-lightweight magnet specially designed and manufactured for ISOL. - Cost efficiency MR system due to air cooling type (equivalent to permanent magnetic). - Patient processing speed of less than 20 minutes.'
Device Information and Specification
CLINICAL APPLICATION
Whole body
CONFIGURATION
Short bore compact
Head, C-spine, L-spine, TMJ, Knee, Shoulder, General purpose, Phased Array System: 4 digital receiver channels (Up to 12 channels)
SYNCHRONIZATION
ECG/peripheral: Optional/yes, respiratory gating
SINGLE/MULTI SLICE
Image reconstruction time (2562 ) : 0.02 s
FOV
40 cm
BORE DIAMETER
or W x H
58 cm diameter
MAGNET WEIGHT
3200 kg
H*W*D
200 x 168 x 187 cm
COOLING SYSTEM TYPE
Air-cooled coil and amplifier
CRYOGEN USE
0.05 L/hr helium
STRENGTH
15 mT/m
5-GAUSS FRINGE FIELD
2.3 m / 3.1 m
Passive and active
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• View the DATABASE results for 'ENCORE 0.5T™' (2).Open this link in a new window

MRI Resources 
Service and Support - MRA - Liver Imaging - Safety Products - Resources - Contrast Enhanced MRI
 
Lung ImagingMRI Resource Directory:
 - Lung Imaging -
 
Lung imaging is furthermore a challenge in MRI because of the predominance of air within the lungs and associated susceptibility issues as well as low signal to noise of the inflated lung parenchyma. Cardiac and respiratory triggered or breath hold sequences allow diagnostic imaging, however a comparable image quality with computed tomography is still difficult to achieve.
Assumptions for lung MRI:
•
Low signal to noise ratio of the inherently low lung proton density.
•
Cardiac and respiratory motion artifacts.
•
Magnetic susceptibility effects of large magnetic field gradients.
•
Very short transverse relaxation times and significant diffusion yielding short T2 (30-70 msec), short T2* (1-3 msec), and additional long T1 relaxation times (1300-1500 msec).
•
The extreme short T2 values are responsible for a fast signal decay during a single shot readout, resulting in blurring.

The current trends in MRI are the use of new imaging technologies and increasingly powerful magnetic fields. Among these technologies are parallel imaging techniques as well as ventilation agents like hyperpolarized helium for the use as an inert inhalational contrast agent to study lung ventilation properties. With hyperpolarized gases clear images of the lungs can be obtained without using a large magnetic field (see also back projection imaging). Single shot sequences (e.g. TSE or Half Fourier Acquisition Single Shot Turbo Spin Echo HASTE) used in lung MR imaging benefits from parallel imaging techniques due to reduced relaxation time effects during the echo train and therefore reduced image blurring as well as reduced motion artifacts.
In the future, more effective contrast agents may provide an alternative solution to the need for high field MRI. Dynamic contrast enhanced MRI perfusion has demonstrated a potential in the diagnosis of pulmonary embolism or to characterize lung cancer and mediastinal tumors. 3D contrast enhanced magnetic resonance angiography of the thoracic vessel.

See also the related poll result: 'MRI will have replaced 50% of x-ray exams by'
 
Images, Movies, Sliders:
 Anatomic Imaging of the Lungs  Open this link in a new window
      

Courtesy of  Robert R. Edelman
 Normal Lung Gd Perfusion MRI  Open this link in a new window
      

Courtesy of  Robert R. Edelman

 MRI Thorax Basal Plane  Open this link in a new window
 
Radiology-tip.comradLung Scintigraphy
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• View the DATABASE results for 'Lung Imaging' (7).Open this link in a new window


• View the NEWS results for 'Lung Imaging' (3).Open this link in a new window.
 
Further Reading:
  Basics:
A safer approach for diagnostic medical imaging
Monday, 29 September 2014   by www.eurekalert.org    
Parallel Lung Imaging(.pdf)
  News & More:
Chest MRI a viable alternative to chest CT in COVID-19 pneumonia follow-up
Monday, 21 September 2020   by www.healthimaging.com    
CT Imaging Features of 2019 Novel Corona virus (2019-nCoV)
Tuesday, 4 February 2020   by pubs.rsna.org    
Polarean Imaging Phase III Trial Results Point to Potential Improvements in Lung Imaging
Wednesday, 29 January 2020   by www.diagnosticimaging.com    
Low Power MRI Helps Image Lungs, Brings Costs Down
Thursday, 10 October 2019   by www.medgadget.com    
Chest MRI Using Multivane-XD, a Novel T2-Weighted Free Breathing MR Sequence
Thursday, 11 July 2019   by www.sciencedirect.co    
Researchers Review Importance of Non-Invasive Imaging in Diagnosis and Management of PAH
Wednesday, 11 March 2015   by lungdiseasenews.com    
New MRI Approach Reveals Bronchiectasis' Key Features Within the Lung
Thursday, 13 November 2014   by lungdiseasenews.com    
MRI techniques improve pulmonary embolism detection
Monday, 19 March 2012   by medicalxpress.com    
  News & More:
Partnership with VIDA to streamline adoption of advanced MRI of the lungs
Monday, 11 September 2023   by www.itnonline.com    
MRI Resources 
Service and Support - Distributors - Coils - Supplies - Lung Imaging - Shielding
 
Chemical Shift ArtifactInfoSheet: - Artifacts - 
Case Studies, 
Reduction Index, 
etc.MRI Resource Directory:
 - Artifacts -
 
Quick Overview
Please note that there are different common names for this artifact.
Artifact Information
NAME
Chemical shift, black boundary, spatial misregistration, relief
DESCRIPTION
Black or bright band
During frequency encoding, fat protons precess slower than water protons in the same slice because of their magnetic shielding. Through the difference in resonance frequency between water and fat, protons at the same location are misregistrated (dislocated) by the Fourier transformation, when converting MRI signals from frequency to spatial domain. This chemical shift misregistration cause accentuation of any fat-water interfaces along the frequency axis and may be mistaken for pathology. Where fat and water are in the same location, this artifact can be seen as a bright or dark band at the edge of the anatomy.
Protons in fat and water molecules are separated by a chemical shift of about 3.5 ppm. The actual shift in Hertz (Hz) depends on the magnetic field strength of the magnet being used. Higher field strength increases the misregistration, while in contrast a higher gradient strength has a positive effect. For a 0.3 T system operating at 12.8 MHz the shift will be 44.8 Hz compared with a 223.6 Hz shift for a 1.5 T system operating at 63.9 MHz.
mri safety guidance
Image Guidance
For artifact reduction helps a smaller water fat shift (higher bandwidth), a higher matrix, an in phase TE or a spin echo technique. Since the misregistration offset is present in the read out axis the patient may be rescanned with this axis parallel to the fat-water interface. Steeper gradient may be employed to reduce the chemical shift offset in mm. Another strategy is to employ specialized pulse sequences such as fat saturation or inversion recovery imaging. Fat suppression techniques eliminate chemical shift artifacts caused by the lack of fat signal.

See also Black Boundary Artifact and Magnetic Resonance Spectroscopy.
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• View the DATABASE results for 'Chemical Shift Artifact' (7).Open this link in a new window

 
Further Reading:
  Basics:
MRI Artifact Gallery
   by chickscope.beckman.uiuc.edu    
  News & More:
What is chemical shift artefact? Why does it occur? How many Hz at 1.5 T?
   by www.revisemri.com    
Abdominal MRI at 3.0 T: The Basics Revisited
Wednesday, 20 July 2005   by www.ajronline.org    
MRI Resources 
Guidance - Quality Advice - Contrast Agents - Fluorescence - Safety Products - Cardiovascular Imaging
 
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