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 'Contrast Medium' 
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Result : Searchterm 'Contrast Medium' found in 1 term [] and 26 definitions []
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News  (6)  Forum  (2)  
 
Contrast MediumForum -
related threadsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
A contrast medium (or contrast agent) is a chemical substance introduced to the anatomical or functional region being imaged, to increase the differences between different tissues or between normal and abnormal tissue, by altering the relaxation times.
The chemical composition of the contrast media determines the specific usage. Similar to nuclear imaging is the intention in development of MR contrast media a high affinity to different organs or even tumors (e.g. necrosis avid contrast agent).
In 'contrast' to nuclear imaging contrast agents MR contrast media do not contain radiopharmaceuticals and the concentrations are about 100 times higher. Nuclear imaging contrast agents are direct contrast agents;; they are directly visible caused by their radioactivity. MR contrast agents affect the targeted tissue; they are indirect contrast agents.
See also Contrast Agents, the info sheet gives an overview and more in-depth information about different types of MRI contrast medium.
 
Images, Movies, Sliders:
 Breast MRI Images T1 Pre - Post Contrast  Open this link in a new window
      
 MRI of the Brain Stem with Temoral Bone and Auditory System  Open this link in a new window
    
SlidersSliders Overview

 
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• Related Searches:
    • MRI Safety
    • Contrast Enhanced MR Venography
    • Liver Imaging
    • Contrast Agents
    • Breast MRI
 
Further Reading:
  Basics:
Analysis of MRI contrast agents
Thursday, 17 November 2022   by www.sciencedaily.com    
Contrast Agents: Safety Profile
   by www.clinical-mri.com    
Questions and Answers on Gadolinium-Based Contrast Agents
Friday, 9 January 2009   by www.fda.gov    
  News & More:
CT contrast reaction raises MRI contrast risk
Tuesday, 22 February 2022   by www.sciencedaily.com    
Polysaccharide-Core Contrast Agent as Gadolinium Alternative for Vascular MR
Monday, 8 March 2021   by www.diagnosticimaging.com    
GE Healthcare expands MRI contrast media product range in Europe with launch of macrocyclic agent ClariscanTM
Wednesday, 1 March 2017   by www.businesswire.com    
Lawson scientists develop commercial imaging product for PET/MRI scanners
Wednesday, 9 December 2015   by www.news-medical.net    
New oxygen-enhanced MRI scan 'helps identify most dangerous tumours'
Thursday, 10 December 2015   by www.dailymail.co.uk    
Contrast MRIs cause claims, concern, over residual metal in brain
Tuesday, 8 December 2015   by www.afr.com    
A Manganese Alternative to Gadolinium for MRI Contrast.
Friday, 4 December 2015   by www.ncbi.nlm.nih.gov    
Searchterm 'Contrast Medium' was also found in the following service: 
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Ultrasound  (9) Open this link in a new window
MRI SafetyMRI Resource Directory:
 - Safety -
 
There are different types of contraindications that would prevent a person from being examined with an MRI scanner. MRI systems use strong magnetic fields that attract any ferromagnetic objects with enormous force. Caused by the potential risk of heating, produced from the radio frequency pulses during the MRI procedure, metallic objects like wires, foreign bodies and other implants needs to be checked for compatibility. High field MRI requires particular safety precautions. In addition, any device or MRI equipment that enters the magnet room has to be MR compatible. MRI examinations are safe and harmless, if these MRI risks are observed and regulations are followed.

Safety concerns in magnetic resonance imaging include:
•
the magnetic field strength;
•
possible 'missile effects' caused by magnetic forces;
•
the potential for heating of body tissue due to the application of the radio frequency energy;
•
the effects on implanted active devices such as cardiac pacemakers or insulin pumps;
•
magnetic torque effects on indwelling metal (clips, etc.);
•
the audible acoustic noise;
•
danger due to cryogenic liquids;
•
the application of contrast medium;
mri safety guidance
MRI Safety Guidance
It is important to remember when working around a superconducting magnet that the magnetic field is always on. Under usual working conditions the field is never turned off. Attention must be paid to keep all ferromagnetic items at an adequate distance from the magnet. Ferromagnetic objects which came accidentally under the influence of these strong magnets can injure or kill individuals in or nearby the magnet, or can seriously damage every hardware, the magnet itself, the cooling system, etc.. See MRI resources Accidents.
The doors leading to a magnet room should be closed at all times except when entering or exiting the room. Every person working in or entering the magnet room or adjacent rooms with a magnetic field has to be instructed about the dangers. This should include the patient, intensive-care staff, and maintenance-, service- and cleaning personnel, etc..
The 5 Gauss limit defines the 'safe' level of static magnetic field exposure. The value of the absorbed dose is fixed by the authorities to avoid heating of the patient's tissue and is defined by the specific absorption rate. Leads or wires that are used in the magnet bore during imaging procedures, should not form large-radius wire loops. Leg-to-leg and leg-to-arm skin contact should be prevented in order to avoid the risk of burning due to the generation of high current loops if the legs or arms are allowed to touch. The patient's skin should not be in contact with the inner bore of the magnet.
The outflow from cryogens like liquid helium is improbable during normal operation and not a real danger for patients.
The safety of MRI contrast agents is tested in drug trials and they have a high compatibility with very few side effects. The variations of the side effects and possible contraindications are similar to X-ray contrast medium, but very rare. In general, an adverse reaction increases with the quantity of the MRI contrast medium and also with the osmolarity of the compound.

See also 5 Gauss Fringe Field, 5 Gauss Line, Cardiac Risks, Cardiac Stent, dB/dt, Legal Requirements, Low Field MRI, Magnetohydrodynamic Effect, MR Compatibility, MR Guided Interventions, Claustrophobia, MRI Risks and Shielding.
Radiology-tip.comradRadiation Safety,  Ionizing Radiation
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Medical-Ultrasound-Imaging.comUltrasound Safety,  Absorbed Dose
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• View the DATABASE results for 'MRI Safety' (42).Open this link in a new window


• View the NEWS results for 'MRI Safety' (13).Open this link in a new window.
 
Further Reading:
  Basics:
MRI Safety
2001   by www.fda.gov    
What MRI Sequences Produce the Highest Specific Absorption Rate (SAR), and Is There Something We Should Be Doing to Reduce the SAR During Standard Examinations?
Thursday, 16 April 2015   by www.ajronline.org    
Contrast Agents: Safety Profile
   by www.clinical-mri.com    
  News & More:
How safe is 7T MRI for patients with neurosurgical implants?
Thursday, 17 November 2022   by healthimaging.com    
Newer Heart Devices Safe During MRI
Monday, 23 August 2004   by www.hospimedica.com    
Study: Face Masks Unsafe in MRI Machines
Wednesday, 13 July 2022   by www.laboratoryequipment.com    
COVID-19: Attention shifts to MRI infection control
Thursday, 9 July 2020   by https://www.auntminnieeurope.com/index.aspx?sec=ser§sub=def§pag=dis§ItemID=619012    
FDA Releases New Guidance On Establishing Safety, Compatibility Of Passive Implants In MR Environments
Tuesday, 16 December 2014   by www.meddeviceonline.com    
Modern Implantable Heart Devices Safe For Use In MRI Scans
Wednesday, 16 March 2005   by www.sciencedaily.com    
MRI Resources 
Veterinary MRI - Movies - Abdominal Imaging - MRI Technician and Technologist Schools - Jobs pool - Fluorescence
 
Nephrogenic Systemic FibrosisForum -
related threads
 
(NSF) Nephrogenic systemic fibrosis is a rare and highly debilitating disorder that involves extensive thickening and hardening of the skin with fibrotic nodules and plaques.
MRI contrast media have very low side effects, but accumulating data indicate that gadolinium-based contrast agents increase the risk for the development of NSF among patients with severe renal insufficiency or renal dysfunction due to the hepato-renal syndrome or in the perioperative liver transplantation period.
Due to this reason, gadolinium contrast agents are now considered contraindicated in patients with an estimated glomerular filtration rate fewer than 30 mL/min/1.73m2. In these patients, avoid use of gadolinium-based contrast agents unless the diagnostic information is essential and not available with non-contrast enhanced magnetic resonance imaging (MRI).

Recognized or possibly associated factors for NSF:
Severe renal failure;
high dose of gadolinium chelate;
high dose of erythropoietin;
high serum phosphate levels;
high serum calcium levels;
major surgery, infection, vascular event;
history of hypothyroidism;
metabolic acidosis.

When administering a gadolinium-based contrast agent, do not exceed the recommended dose and allow a sufficient period of time for elimination of the contrast medium from the body prior to any readminstration. Screen all patients for renal dysfunction by obtaining a history and/or laboratory tests.

See also Contrast Medium, Adverse Reaction, MRI Risks, MRI Safety, Ionic Intravenous Contrast Agents, Nonionic Intravenous Contrast Agents, and Contraindications.
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• View the DATABASE results for 'Nephrogenic Systemic Fibrosis' (13).Open this link in a new window


• View the NEWS results for 'Nephrogenic Systemic Fibrosis' (8).Open this link in a new window.
 
Further Reading:
  Basics:
Important Drug Warning for Gadolinium-Based Contrast Agents
Wednesday, 12 September 2007   by www.ismrm.org    
European Medicines Agency makes recommendations to minimise risk of nephrogenic systemic fibrosis with gadolinium-containing contrast agents
Friday, 20 November 2009   by www.ema.europa.eu    
Gadolinium-based MR Contrast Agents and Nephrogenic Systemic Fibrosis
Thursday, 1 March 2007   by radiology.rsna.org    
NSF-Active and NSF-Inert Species of Gadolinium: Mechanistic and Clinical Implications
Friday, 27 June 2008   by www.ajronline.org    
  News & More:
Questions and Answers on Gadolinium-Based Contrast Agents
Friday, 9 January 2009   by www.fda.gov    
Searchterm 'Contrast Medium' was also found in the following services: 
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News  (6)  Forum  (2)  
 
Adverse Reaction
 
Any abnormal reaction of a patient to an examination or procedure, like for example claustrophobia or side effects of MRI contrast agents.
A claustrophobic attack is MRI scanner dependent and more rare with an open MRI. An adverse reaction with magnetic resonance imaging contrast medium is very infrequent. In general, adverse reactions increase with the quantity of contrast media (usual dose of paramagnetic contrast agents is 0.1 mmol/kg) and also with the osmolarity of the compound.
Most frequently encountered adverse reactions are heat sensation, dizziness, nausea, hypotension due to vasodilatation, which can progress to hypotensive shock and anaphylactic reactions.
See also MRI Safety, Contrast Enhanced MRI, Breast MRI, and Cardiac MR imaging.
Radiology-tip.comradSafety of Contrast Agents,  Anaphylactoid Reaction
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Medical-Ultrasound-Imaging.comUltrasound Contrast Agent Safety
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• View the DATABASE results for 'Adverse Reaction' (8).Open this link in a new window

 
Further Reading:
  Basics:
Questions and Answers on Gadolinium-Based Contrast Agents
Friday, 9 January 2009   by www.fda.gov    
Contrast Agents: Safety Profile
   by www.clinical-mri.com    
  News & More:
CT contrast reaction raises MRI contrast risk
Tuesday, 22 February 2022   by www.sciencedaily.com    
Searchterm 'Contrast Medium' was also found in the following service: 
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Ultrasound  (9) Open this link in a new window
Blood Pool AgentsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Blood pool agents (intravascular contrast agents) remain in the blood for a prolonged time compared with conventional contrast agents, which diffuse quickly into the interstitial space. Magnetic resonance angiography (MRA), cardiovascular imaging, or contrast enhanced MRIs are possible over an hour or more. This advantage over conventional MRI contrast media allows also higher resolution MRA of several territories using respiratory or cardiac gating techniques with a single contrast bolus.
Different types of blood pool contrast agents:
Blood pool MRI contrast agents with their longer intravascular circulation can be designed to be targeted to necrotic myocardium, to assess myocardial viability, or tumor directed to provide better diagnostic information for various tumors. A disadvantage of the use of blood pool agents for MRA is that the separation of arteries and veins is more difficult because they are present in both and the overlapping of those vessels is disturbing. This can be solved by e.g. different MIP segmentation algorithms.

See also Necrosis Avid Contrast Agent, Tumor Specific Agents, Feruglose, Gadofosveset Trisodium (Vasovist), Ultrasmall Superparamagnetic Iron Oxide and Contrast Medium.
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• View the DATABASE results for 'Blood Pool Agents' (16).Open this link in a new window


• View the NEWS results for 'Blood Pool Agents' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Ablavar Prescribing Information
   by www.ablavar.com    
Lantheus Medical Imaging, Inc. Launches ABLAVARâ„¢ (Gadofosveset Trisodium), a New Diagnostic Magnetic Resonance Angiography Agent
Wednesday, 20 January 2010   by www.radiopharm.com    
Blood-Pool Imaging Using Technetium-99m-Labeled Liposomes(.pdf)
   by jnm.snmjournals.org    
  News & More:
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
MAGNETIC RESONANCE IMAGING OF FOCAL LIVER LESIONS(.pdf)
2002
MRI Resources 
Raman Spectroscopy - MRCP - Jobs - Societies - Pacemaker - Functional MRI
 
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