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 'Code 7228' 
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Result : Searchterm 'Code 7228' found in 1 term [] and 3 definitions []
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Code 7228InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Code 7228, generic name: Ferumoxytol, central moiety: Fe
Code 7228 is the code name for a substance in the development pipeline (AMAG Pharmaceuticals, Inc.) for use as a contrast agent in magnetic resonance angiography (MRA). Ferumoxytol, as a true blood pool agent, resides in the vascular space for an extended period of time and does not leak out into adjacent tissues like currently used gadolinium-based contrast agents. The product is being evaluated in MRA applications for the detection of blood flow in the heart muscle, in exploratory studies for the diagnosis of vulnerable plaque and as a next generation lymph node agent.
Code 7228 is currently in approval phase for use as an iron replacement therapeutic in chronic kidney disease patients receiving erythropoetin.
It is presently contemplated that Ferumoxytol will compete with the contrast agents Vasovist™ from EPIX Pharmaceuticals, Inc. and NC100150 Injection from Nycomed Amersham.

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Ferumoxytol
   by www.amagpharma.com    
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MRCP - Brain MRI - - Crystallography - Liver Imaging - Bioinformatics
 
AMAG Pharmaceuticals, Inc.MRI Resource Directory:
 - Developers -
 
www.amagpharma.com The company changed its name from Advanced Magnetics, Inc. to AMAG Pharmaceuticals, Inc. in July 2007.
AMAG Pharmaceuticals, Inc., a biopharmaceutical company, developed and manufactured organ-specific diagnostic contrast agents that provide clearer images during magnetic resonance imaging (MRI) tests used to detect tumors and other abnormalities.
The company had two MRI related products on the market: Feridex I.V. (for the diagnosis of liver lesions) and GastroMARK (used for bowel and abdominal MR imaging). In November 2008, AMAG Pharmaceuticals, Inc. decided to discontinue the manufacturing of Feridex. The development of Combidex as a contrast agent for lymph disease has also been stopped.
The Company has now two commercial products: Feraheme® and GastroMARK®. Feraheme® is the trade name of Ferumoxytol (formerly Code 7228) and is indicated for the treatment of iron deficiency anemia. Feraheme® is also being developed as a diagnostic agent for vascular-enhanced magnetic resonance imaging (MRI) to assess peripheral arterial disease.

Product Information
TRADE NAME
(LOCAL DISTRIBUTION)
FOR SALE FOR SALE /
DEVELOPMENT
DEVELOPMENT
Combidex® -
Feridex® -
GastroMARK®
Feraheme®

Contact Information
MAIL AMAG Pharmaceuticals, Inc.
61 Mooney St.
Cambridge, MA 02138
USA
PHONE +1-617-497-2070
FAX +1-617-547-2445
E-MAIL contactus@amagpharma.com
ONLINE www.amagpharma.com

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• View the NEWS results for 'AMAG Pharmaceuticals, Inc.' (7).Open this link in a new window.
 
Further Reading:
  Basics:
Advanced Magnetics, Inc. Announces Name Change to AMAG Pharmaceuticals, Inc.
Tuesday, 24 July 2007   by salesandmarketingnetwork.com    
Ferumoxytol
   by www.amagpharma.com    
AMAG Pharmaceuticals Inc. Q4 2008 Earnings Call Transcript
Friday, 27 February 2009   by seekingalpha.com    
  News & More:
The demise of Combidex - Sinerem
Wednesday, 24 March 2010   by www.wellsphere.com    
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FerumoxytolInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Ferumoxytol is a product candidate for iron replacement therapy in the development pipeline of AMAG Pharmaceuticals Inc, formerly known as Code 7228.
Ferumoxytol has a long blood half-life and may be useful as a blood pool agent in a wide range of applications in MRI. Ferumoxytol is a true intravascular contrast agent that remains in the blood stream for an extended period of time.
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• View the NEWS results for 'Ferumoxytol' (3).Open this link in a new window.
 
Further Reading:
  News & More:
Diffusion-weighted MRI shows promise as a radiation-free alternative for pediatric tumor staging
Wednesday, 19 February 2014   by www.2minutemedicine.com    
Rienso® (Ferumoxytol) Launched in Europe for the Treatment of Iron Deficiency Anemia in Adult Patients with Chronic Kidney Disease Launch Triggers $15 Million Milestone Payment to AMAG
Monday, 5 November 2012   by ir.amagpharma.com    
Searchterm 'Code 7228' was also found in the following service: 
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MS-325Forum -
related threadsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
MS-325 is the formerly code name of gadofosveset trisodium (new trade name Vasovist). MS-325 belongs to a new class of blood pool agents for magnetic resonance angiography (MRA) to diagnose vascular disease. Gadofosveset trisodium has ten times the signal-enhancing power of existing contrast agents as well as prolonged retention in the blood. This enables the rapid acquisition of high resolution MRA's using standard MRI machines.
Gadofosveset trisodium, which is gadolinium-based, stays in the blood stream as a result of transient binding to albumin. Albumin binding offers an additional benefit beyond localization in the blood pool. The contrast agent begins to spin much more slowly, at the rate albumin spins, causing a relaxivity gain that produces a substantially brighter signal than would be possible with freely circulating gadolinium. MS-325 is an intravascular contrast agent intended for use in MRI as an aid in diagnosing aortoiliac occlusive disease in patients with known or suspected peripheral vascular disease (PVD) or abdominal aortic aneurysm (AAA).
Currently clinical trials completed for peripheral vascular disease and coronary artery disease. Additional trials are also being conducted to evaluate MS-325 as an aid in diagnosing breast cancer and suggested that it might be feasible to combine the use of MS-325, injected during peak stress, with delayed high-resolution imaging to identify myocardial perfusion defects.
Vasovist (MS-325) would compete with the contrast agents Ferumoxytol (Code 7228) from AMAG Pharmaceuticals, Inc. and NC100150 Injection from Nycomed Amersham, but their further development is uncertain.
Partners in development: EPIX Pharmaceuticals, Inc., Mallinckrodt Inc., and Bayer Schering Pharma AG. Bayer Schering Pharma has the worldwide marketing rights for the product.
Formerly known under the Mallinckrodt trademark name, AngioMARK®.
See also Classifications, Characteristics, etc.
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• View the NEWS results for 'MS-325' (10).Open this link in a new window.
 
Further Reading:
  News & More:
EPIX Medical's new multimedia Web site features AngioMARK images in 3D
Friday, 5 March 1999
MRI technology combined with contrast agent optimizes diagnosis of cardiovascular disease
1999
MRI Resources 
MR Myelography - Shielding - Health - Open Directory Project - Contrast Enhanced MRI - Cochlear Implant
 
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