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Result : Searchterm 'Brain MRI' found in 1 term [] and 13 definitions [], (+ 13 Boolean[] results
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Searchterm 'Brain MRI' was also found in the following services: 
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News  (170)  Resources  (28)  Forum  (3)  
 
Perfusion AgentsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Any molecule used to measure organ perfusion in conjunction with imaging.
Characteristics of good perfusion agents:
to be admitted by the perfused tissue in proportion to perfusion,
to remain strictly intravascular, or
diffuse freely throughout the tissue of interest.
Perfusion agents used in MRI are small Gd-chelates (they do not cross blood brain barrier, but extravasate quickly into extracellular space in other organs) and SPIOS.
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• View the NEWS results for 'Perfusion Agents' (3).Open this link in a new window.
 
Further Reading:
  Basics:
EVALUATION OF HUMAN STROKE BY MR IMAGING
2000
MRI Resources 
Process Analysis - Crystallography - Intraoperative MRI - Knee MRI - Musculoskeletal and Joint MRI - DICOM
 
Clariscan™InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
Clariscan™ (gadoteric acid), a macrocyclic and ionic gadolinium-based contrast agent has newly been approved using the decentralized procedure with marketing authorization in place in Norway. It will be introduced by GE Healthcare to European countries in 2017.


See also: Paramagnetic Contrast Agents, Contrast Medium, Extracellular Fluid Agents, Ionic Intravenous Contrast Agents, Nonionic Intravenous Contrast Agents, Chelate, Adverse Reaction and Nephrogenic Systemic Fibrosis.

See also the related poll result: 'The development of contrast agents in MRI is'

Drug Information and Specification
NAME OF COMPOUND Gadoteric Acid
DEVELOPER GE Healthcare
CENTRAL MOIETY Gadolinium
CONTRAST EFFECT T1, Predominantly positive enhancement
RELAXIVITY R1 3.1, R2 3.6, B0 = 1.5 Tesla
PHARMACOKINETIC Intravascular, extracellular, renal excretion
OSMOLALITY 1350 mOsm.kg-1
CONCENTRATION 0.5 mmol /mL
DOSAGE 0.1 mmol/kg / 0.2 ml/kg
INDICATION Brain, spine and associated tissues
PRESENTATIONS Glass vial 5, 10, 15, 20 mL
Glass bottle 50, 100 mL
Polypropylene bottles 50, 100 mL
Plastic (Crystal Clear Polymer) pre-filled syringes 10, 15, 20 mL
DEVELOPMENT STAGE Sale starts 2017 in Norway, Sweden, UK. Global launch is planned.
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT


[ Clariscan™ was also the name of an contrast agent under development by Amersham Health around the year 2000 which doesn't reach the market: '(An iron-based contrast agent with large molecular size, which prevents diffusion into body tissues and was developed for MR imaging of the liver (taken up by macrophages), tumor microvasculature and microvessel permeability. The blood half live of the particles with 11-20 nm diameter is 3-4 hours. See also NC100150 Injection and Ultrasmall Superparamagnetic Iron Oxide)'.
The new developed Clariscan™ by GE Healthcare is a totally different contrast agent.]
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• View the DATABASE results for 'Clariscan™' (6).Open this link in a new window

 
Further Reading:
  Basics:
SUMMARY OF PRODUCT CHARACTERISTICS
Wednesday, 22 February 2017   by www.mhra.gov.uk    
  News & More:
GE Healthcare expands MRI contrast media product range in Europe with launch of macrocyclic agent ClariscanTM
Wednesday, 1 March 2017   by www.businesswire.com    
MRI Resources 
Brain MRI - - General - Universities - Research Labs - MRI Centers
 
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