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Mole
 
The mole is the basic unit of substance.
Definition: The amount of substance that contains as many elementary units as there are atoms in 0.012 kg of carbon-12.
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Molecular Imaging
 
Molecular Imaging is a new diagnostic discipline to visualize biological processes.
Molecular magnetic resonance imaging (mMRI) offers the potential to image tissues at the cellular and subcellular level. Targeted MR contrast agents enhance the diagnostic specificity and range of molecular magnetic resonance imaging.
Other modalities that can be used for noninvasive molecular imaging:
•
Ultrasound;
•
optical imaging;
•
positron emission tomography (PET);
•
single photon emission computed tomography (SPECT).


See also Nanoparticle, Monocrystalline Iron Oxide Nanoparticle, Polycrystalline Iron Oxide Nanoparticles, Liposomes, Monoclonal Antibodies, Bimodal Imaging, Tumor Specific Agents, and Intracellular Contrast Agents.
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Further Reading:
  Basics:
Multimodal Nanoparticles for Quantitative Imaging(.pdf)
Tuesday, 13 December 2011   by alexandria.tue.nl    
Molecular Magnetic Resonance Imaging(.pdf)
2005   by www.medical.siemens.com    
  News & More:
Smarter MRI diagnosis with nano MRI lamp
Monday, 6 February 2017   by www.eurekalert.org    
Molecular MRI technique gives early indication of cancer treatment effectiveness
Monday, 11 April 2016   by www.healthimaging.com    
Molecular imaging and radiochemistry: the importance of instrumentation. An interview with Professor Bjorn Wangler
Thursday, 4 February 2016   by www.news-medical.net    
Positron Emission Tomographic Imaging in Stroke
Monday, 28 December 2015   by www.ncbi.nlm.nih.gov    
Potential and Limitations of Oxygen-17 MR Perfusion Measurements
Monday, 1 March 2004   by www.case.edu    
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Molecule
 
Structure formed of atoms of various elements.
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• View the DATABASE results for 'Molecule' (41).Open this link in a new window

 
Further Reading:
  Basics:
Carbon molecule with a charge could be tomorrow's semiconductor
Tuesday, 9 September 2008   by www.brightsurf.com    
  News & More:
A powder to enhance NMR signals
Thursday, 12 December 2013   by phys.org    
Diffusion-Weighted MRI in the Body: Applications and Challenges in Oncology
Friday, 1 June 2007   by www.ajronline.org    
Researchers create novel way to enhance MRI
Tuesday, 30 April 2013   by www.news-medical.net    
Monoclonal AntibodiesInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(McAb) Monoclonal antibodies are used for tumor detection and localization in nuclear medicine. In MRI, monoclonal antibodies labeled with paramagnetic or superparamagnetic particles are being studied for targeting tumors, for example contrast agent containing gadolinium attached to a targeting antibody. The antibody would bind to a specific target (e.g., a metastatic melanoma cell) while the gadolinium would increase the MRI signal. Further developments are MRI contrast agents that specifically target glucose receptors on tumor cells; coupled with the high spatial resolution of high field MRI devices, these agents have potentials to detect small tumor foci.
The monoclonal antibody manufacturers produce a wide variety of ligands, which can be directed against a multiplicity of pathologic molecular targets. MRI enhanced with targeted contrast agents can be used for molecular imaging.
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Further Reading:
  News & More:
Measuring mAbs with magnetic resonance can help regulatory testing
Thursday, 23 April 2015   by www.biopharma-reporter.com    
Repligen - Eyeing Sustainable Profitability
Monday, 31 October 2011   by www.rttnews.com    
Monocrystalline Iron Oxide NanoparticleInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: MION, central moiety: Fe3+/Fe2+, relaxivity: r1=3.7, r2=6.5, B0=0.47T
MIONs are under development (preclin.) as contrast agents (taken up by the RES) for MR angiography, MR lymphography, tumor detection and detection of infarctioned tissue. Also called monodisperse iron oxide nanoparticles or nanocompounds.
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• View the DATABASE results for 'Monocrystalline Iron Oxide Nanoparticle' (3).Open this link in a new window

 
Further Reading:
  Basics:
Biomedical scientist to test nanoparticles as early cancer detection agent
Monday, 28 October 2002
  News & More:
Turning up the heat on cancer
Thursday, 22 November 2007   by www.rsc.org    
Vascular Filters of Functional MRI: Spatial Localization Using BOLD and CBV Contrast
MRI Resources 
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