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MRI Forum: Best pulse sequences for spin ...
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Karen Lesley

Sat. 21 May.11,
16:03
Best pulse sequences for spinal cord demyelination?
Hi all. I wonder if you can help? A friend has asked me to recommend the best protocols to detect demyelination. She is about to pay a fortune for a private 3T scan and doesn't want to waste her money. Problem is, although I know a fair bit about the brain, I know next to nothing about the spinal cord! I understand that FLAIR is not optimal in the spinal cord, but I'm getting mixed messages about what is from my reading. Is it FSE?! Any advice really gratefully received! Thanks :-)
Katelin Lyons

Fri. 27 May.11,
10:07
 Small spinal cord lesions, even if clinically significant, can be due to the low sensitivity of some pulse sequences. Demyelinating lesions are better seen on STIR-FSE images, on which the number of lesions are significantly higher than on FSE, while the FSE and CSE images show approximately equal numbers of lesions.So as STIR-FSE has high sensitivity to demyelinating lesions,it can be considered quite specific and should be included in spinal MRI for assessment of suspected demyelinating disease.
Karen Lesley

Sun. 29 May.11,
09:51
 Thank you so much for your response Katelin :-) I will pass the info on. Karen.
Katelin Lyons

Tue. 31 May.11,
04:41
 No issues Karen!

I'm glad that the information helped you. Do feel free to raise any further query, if you have.
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