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 'Gadolite® Oral Suspension' 
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Gadolite® Oral SuspensionInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
An oral suspension of synthetic crystalline aqueous orange-flavored MRI contrast agent to enhance delineation of the bowel. Gadolite contains gadolinium, a lanthanide metal with paramagnetic characteristics. The toxic Gd is bound to become inert, along with water, inside a zeolite crystalline lattice structure. Gadolite gives a bright signal, and provides improved definition of the gastrointestinal tract from adjacent tissues.
Pharmacyclics receives an approvable letter from the FDA for Gadolite® Oral Suspension and in the United Kingdom an European marketing agreement signed with E-Z-Em, Ltd. in Dec. 1996.

Drug Information and Specification
NAME OF COMPOUND Gadolinium zeolite, Gadolinium chloride hexahydrate
DEVELOPER Pharmacyclics, Inc.
CENTRAL MOIETY Gd2+
CONTRAST EFFECT T1, Predominantly positive enhancement
RELAXIVITY Paramagnetic
PHARMACOKINETIC Gastrointestinal
OSMOLALITY
CONCENTRATION
DOSAGE
PREPARATION Oral suspension
INDICATION Bowel marking
DEVELOPMENT STAGE For sale
DISTRIBUTOR See below
PRESENTATION Suspension
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!

Distribution Information
TERRITORY TRADE NAME DEVELOPMENT
STAGE
DISTRIBUTOR
USA
Canada
Mexico
EU
Gadolite® Oral Suspension for sale E-Z-EM

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Further Reading:
  Basics:
Chembytes e-zine, Special agentsOpen this link in a new window
1998
  News & More:
CONTRAST AGENTS IN MRI(.pdf)Open this link in a new window
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E-Z-EM, Inc.MRI Resource Directory:
 - Manufacturers -
 
www.ezem.com

[This entry is marked for removal.]

E-Z-EM, Inc. is headquartered in New York and develops, manufactures and markets diagnostic imaging products used by radiologists like the MRI bowel marker Gadolite® Oral Suspension.
In addition to medical diagnostics systems, the company's products include MR-compatible interventional devices, such as biopsy needles. E-Z-EM is also a third-party contract manufacturer of contrast media .
Bracco Diagnostics, Inc. , the US-based subsidiary of Bracco Imaging S.p.A. and part of the Bracco Group, announced in Oct. 2007 that it has entered into a merger agreement to acquire E-Z-EM, Inc. (NASDAQ: EZEM) for a total consideration of about $ 240 million . Upon completion of the procedure and subject to the approval of the regulatory authorities, Bracco Diagnostics Inc. will incorporate E-Z-EM.


Product Information
TRADE NAME
(LOCAL DISTRIBUTION)
FOR SALE FOR SALE /
DEVELOPMENT
DEVELOPMENT
Gadolite® Oral Suspension ?

Contact Information
MAIL E-Z-EM, Inc.
Westbury, New York
USA
PHONE +1-800-544-4624
ONLINE www.ezem.com
CONTACT INFO PAGE http://www.ezem.com/contact
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Further Reading:
  Basics:
BRACCO DIAGNOSTICS INC. TO ACQUIRE E-Z-EM Combination Brings Together Two Leading Brands in the Diagnostic Imaging MarketOpen this link in a new window
Tuesday, 30 October 2007   by www.bracco.com    
 •• There is 1 news about 'E-Z-EM, Inc.'.
Pharmacyclics, Inc.MRI Resource Directory:
 - Manufacturers -
 
www.pcyc.com Pharmacyclics is a pharmaceutical company developing novel agents to improve current therapeutic approaches to cancer, cardiovascular diseases, and inflammation. The company's proprietary products are derived from its core technology in biometallic chemistry. These products under development are based upon small molecules, which bind metals in a unique way and are capable of capturing and focusing forms of energy used in a variety of medical applications. The company has one product in registration with the FDA, Gadolite® Oral Suspension, a contrast agent for imaging the gastrointestinal tract; two products in clinical development, Gd-Tex (Motexafin gadolinium), a radiation sensitizer, Lu-Tex, a photosensitizer; and several compounds in preclinical development.

Product Information
TRADE NAME
(LOCAL DISTRIBUTION)
FOR SALE FOR SALE /
DEVELOPMENT
DEVELOPMENT
Gadolite® Oral Suspension
Motexafin Gadolinium

Contact Information
MAIL Pharmacyclics Inc.
995 East Arques Avenue
94085 Sunnyvale, California
USA
PHONE +1-408-774-0330
FAX +1-408-774-0340
E-MAIL info@pcyc.com
ONLINE www.pcyc.com
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Further Reading:
  Basics:
Market for GI MRI contrast agents may get crowded as approvals nearOpen this link in a new window
Wednesday, 8 January 1997   by www.consultantlive.com    
  News & More:
Pharmacyclics Receives Non-Approvable Letter from the FDA for Xcytrin for the Treatment of Lung Cancer Brain MetastasesOpen this link in a new window
Friday, 21 December 2007   by www.prnewswire.com    
Texaphyrin Compounds Visualize Vulnerable PlaqueOpen this link in a new window
Friday, 4 June 2004   by www.medinews.com    
 •• There are 5 news about 'Pharmacyclics, Inc.'.
MRI Resources  
Resources - Sequences - Distributors - Breast Implant - MR Myelography - Safety Training
 
Gadolinium ZeoliteInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(Gadolite® oral Suspension) An oral paramagnetic MRI contrast agent to enhance delineation of the bowel. Zeolites are hydrated aluminosilicates with large holes that can provide a temporary home for guest molecules like gadolinium. Zeolites modified with Gd (III) are effective positive MRI contrast agents for gastrointestinal application.

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Further Reading:
  Basics:
Chembytes e-zine, Special agentsOpen this link in a new window
1998
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