A method used to trace the motion or flow of tissue. Nuclei will retain their magnetic orientation for a time on the order of T1 even in the presence of motion. Thus, if the nuclei in a given region have their spinorientation changed, the altered spins will serve as a 'tag' to trace the motion for a time on the order of T1 of any fluid that may have been in the tagged region.
(DENSE) Displacement Encoding with Stimulated Echoes is a functional cardiac MRIpulse sequence, used to create maps of myocardial displacement with high resolution.
The DENSE magnitude images produce black blood images to show better myocard-blood contrast and to reduce motion artifacts.
(TOF) The time of flight angiography is used for the imaging of vessels. Usually the sequence type is a gradient echosequences with short TR, acquired with slices perpendicular to the direction of blood flow.
The source of diverse flow effects is the difference between the unsaturated and presaturated spins and creates a bright vascular image without the invasive use of contrast media. Flowing blood moves unsaturated spins from outside the slice into the imaging plane. These completely relaxed spins have full equilibriummagnetization and produce (when entering the imaging plane) a much higher signal than stationary spins if a gradient echo sequence is generated. This flow related enhancement is also referred to as entry slice phenomenon, or inflow enhancement.
Performing a presaturationslab on one side parallel to the slice can selectively destroy the MR signal from the in-flowing blood from this side of the slice. This allows the technique to be flow direction sensitive and to separate arteriograms or venograms. When the local magnetization of moving blood is selectively altered in a region, e.g. by selective excitation, it carries the altered magnetization with it when it moves, thus tagging the selected region for times on the order of the relaxation times.
For maximum flow signal, a complete new part of blood has to enter the slice every repetition (TR) period, which makes time of flight angiography sensitive to flow-velocity. The choice of TR and slice thickness should be appropriate to the expected flow-velocities because even small changes in slice thickness influences the performance of the TOF sequence.
The use of sequential 2 dimensional Fourier transformation (2DFT) slices, 3DFT slabs, or multiple 3D slabs (chunks) are depending on the coverage required and the range of flow-velocities.
3D TOF MRA is routinely used for evaluating the Circle of Willis.
A method of tracking moving spins after tagging them (locally altering their magnetization). The moving spins are then imaged at some time after tagging to show where the bolus (the small tagged volume of
spins) has moved in the imaging plane.