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Result : Searchterm 'Liver Imaging' found in 1 term [] and 13 definitions [], (+ 14 Boolean[] results
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Superparamagnetic Iron OxideInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
(SPIO) Relatively new types of MRI contrast agents are superparamagnetic iron oxide-based colloids (median diameter greater than 50nm). These compounds consist of nonstoichiometric microcrystalline magnetite cores, which are coated with dextrans (in ferumoxide) or siloxanes (in ferumoxsil). After injection they accumulate in the reticuloendothelial system (RES) of the liver (Kupffer cells) and the spleen. At low doses circulating iron decreases the T1 time of blood, at higher doses predominates the T2* effect.
SPIO agents are much more effective in MR relaxation than paramagnetic agents. Since hepatic tumors either do not contain RES cells or their activity is reduced, the contrast between liver and lesion is improved. Superparamagnetic iron oxides cause noticeable shorter T2 relaxation times with signal loss in the targeted tissue (e.g., liver and spleen) with all standard pulse sequences. Magnetite, a mixture of FeO and Fe2O3, is one of the used iron oxides. FeO can be replaced by Fe3O4.
Use of these colloids as tissue specific contrast agents is now a well-established area of pharmaceutical development. Feridex®, Endorem™, GastroMARK®, Lumirem®, Sinerem®, Resovist® and more patents pending tell us that the last word in this area is not said.
Some remarkable points using SPIO:
•
A minimum delay of about 10 min. between injection (or infusion) and MR imaging, extends the examination time.
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Cross-section flow void in narrow blood vessels may impede the differentiation from small liver lesions.
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Aortic pulsation artifacts become more pronounced.


See also Superparamagnetism, Superparamagnetic Contrast Agents and Classifications, Characteristics, etc..
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• Related Searches:
    • Superparamagnetic Contrast Agents
    • Reticuloendothelial Contrast Agents
    • Superparamagnetism
    • Intracellular Contrast Agents
    • Hepatobiliary Contrast Agents
 
Further Reading:
  Basics:
IMAGE CONTRAST IN MRI(.pdf)
   by www.assaftal.com    
  News & More:
How to stop using gadolinium chelates for magnetic resonance imaging: clinical-translational experiences with ferumoxytol
Saturday, 5 February 2022   by www.ncbi.nlm.nih.gov    
Polysaccharide-Core Contrast Agent as Gadolinium Alternative for Vascular MR
Monday, 8 March 2021   by www.diagnosticimaging.com    
Poly (dopamine) coated superparamagnetic iron oxide nanocluster for noninvasive labeling, tracking, and targeted delivery of adipose tissue-derived stem cells
Tuesday, 5 January 2016   by www.nature.com    
Longitudinal MRI contrast enhanced monitoring of early tumour development with manganese chloride (MnCl2) and superparamagnetic iron oxide nanoparticles (SPIOs) in a CT1258 based in vivo model of prostate cancer
Wednesday, 11 July 2012   by www.biomedcentral.com    
Searchterm 'Liver Imaging' was also found in the following services: 
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T1W High Resolution Isotropic Volume ExaminationInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(THRIVE) THRIVE is an optimized fast T1 weighted 3 dimensional imaging technique combining sensitivity encoding, large volume coverage and uniform fat suppression. THRIVE improves for example dynamic liver, small bowel, breast, prostate and pancreas MRI, providing isotropic images with high resolution in short breath-hold times.
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• View the DATABASE results for 'T1W High Resolution Isotropic Volume Examination' (3).Open this link in a new window

MRI Resources 
Breast Implant - Education - Mobile MRI Rental - Portals - Cochlear Implant - Intraoperative MRI
 
Volumetric Interpolated Breath Hold ExaminationInfoSheet: - Sequences - 
Intro, 
Overview, 
Types of, 
etc.
 
(VIBE) A T1 weighted 3D FLASH breath hold technique with fat selective prepulse.
Used for dynamic liver, pancreas, pelvis, thorax, orbita imaging and MR colonoscopy.
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Further Reading:
  Basics:
The Effects of Breathing Motion on DCE-MRI Images: Phantom Studies Simulating Respiratory Motion to Compare CAIPIRINHA-VIBE, Radial-VIBE, and Conventional VIBE
Tuesday, 7 February 2017   by www.kjronline.org    
MRI techniques improve pulmonary embolism detection
Monday, 19 March 2012   by medicalxpress.com    
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