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Result : Searchterm 'Liver Imaging' found in 1 term [] and 13 definitions [], (+ 14 Boolean[] results
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Fast Acquisition with Multiphase EFGRE3DInfoSheet: - Sequences - 
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etc.
 
(FAME) The FAME MRI technique uses a 3dimensional fast SPGR pulse sequence to acquire high resolution images. With its short scan time, FAME is useful for dynamic liver imaging with multiple phases.
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GN-1140InfoSheet: - Contrast Agents - 
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Short name: GN-1140, chemical compound: Gd-DTPA-DeA, central moiety: Gd, phase: II
Gd-DTPA-DeA [Welfide Corp., Osaka, Japan], a paramagnetic MR contrast agent with hepatobiliary excretion is under development for liver imaging. This hydrophilic gadolinium chelate is a derivative of Gd-DTPA.
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Hepatobiliary ChelatesInfoSheet: - Contrast Agents - 
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Characteristics, 
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Hepatobiliary chelates used in MRI are paramagnetic contrast agents consisting of a metal ion bound to an organic ligand. Paramagnetic metal ions such as gadolinium improve the MRI signal, but the toxicity of these uncomplexed metal ions makes the use of a chelate to bind the metal ion essential. Due to the hepatocyte uptake of this chelate complex, the different contrast between normal parenchyma and liver lesions improves the detection and characterization of specific diseases. In addition, the hepatobiliary excretion allows the assessment of the hepatobiliary system.
Chelates for hepatobiliary imaging: MultiHanceĀ® (Gadobenate Dimeglumine), TeslascanĀ® (Mangafodipir Trisodium), Gd-HIDA, Cr-HIDA, and Fe-EHPG IronIII or other derivatives.

See also Hepatobiliary Contrast Agents, Liver Imaging.
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Liver Acquisition with Volume AcquisitionInfoSheet: - Sequences - 
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(LAVA) The MRI technique LAVA is based on a 3 dimensional spoiled gradient echo pulse sequence. The optimized inversion pulse and a new fat suppression technique (called segmented special) provides enhanced image contrast and uniform fat suppression. Array spatial sensitivity encoding technique (ASSET) with partial data filling and shorter TR/TE enables to use short breath holds for dynamic liver imaging with multiple phases.
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Further Reading:
  Basics:
MR Field Notes
   by www.gehealthcare.com    
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ResovistĀ®InfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
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etc.MRI Resource Directory:
 - Contrast Agents -
 
ResovistĀ® is an organ-specific MRI contrast agent, used for the detection and characterization of especially small focal liver lesions.
ResovistĀ® consists of superparamagnetic iron oxide (SPIO) nanoparticles coated with carboxydextran, which are accumulated by phagocytosis in cells of the reticuloendothelial system (RES) of the liver. The uptake of ResovistĀ® Injection in the reticuloendothelial cells results in a decrease of the signal intensity of normal liver parenchyma on both T2- and T1 weighted images.
Most malignant liver tumors do not contain RES cells and therefore do not uptake the iron particles. The resulting imaging effect is an improved contrast between the tumor (bright) and the surrounding tissue (dark).
ResovistĀ® can be injected as an intravenous bolus, which allows immediate imaging of the liver and reduces the overall examination time. A dynamic imaging strategy after bolus injection supports to characterize lesions. In comprehensive clinical trials, it demonstrated an excellent safety profile.
In 2001, ResovistĀ® was approved for the European market.

See also Superparamagnetic Iron Oxide.

ResovistĀ® competed with Primovistā„¢, the other liver imaging agent of Bayer Schering Pharma AG. Due to this reason, the production of ResovistĀ® has been abandoned in 2009.
Drug Information and Specification
NAME OF COMPOUND
Ferrixan [Ferucarbotran], carboxydextran coated iron oxide nanoparticles
CENTRAL MOIETY
Fe2+
CONTRAST EFFECT
T2/T1, Predominantly negative enhancement
r1=25.4, r2=151,
PHARMACOKINETIC
RES-directed
333 mosm/kg
CONCENTRATION
0.5 mol Fe/L
DOSAGE
Less than 60 kg = 0.9 ml, greater than 60 kg = 1.4 ml
PREPARATION
Finished product
INDICATION
Liver lesions
DISTRIBUTOR
See below
PRESENTATION
Pre-filled syringes of 0.9 and 1.4 mL
DO NOT RELY ON THE INFORMATION PROVIDED HERE, THEY ARE
NOT A SUBSTITUTE FOR THE ACCOMPANYING PACKAGE INSERT!
Distribution Information
TERRITORY
TRADE NAME
DEVELOPMENT
STAGE
DISTRIBUTOR
USA
ResovistĀ®
?
-
Japan
ResovistĀ®
approved
-
EU
ResovistĀ®
approved
-
Australia
ResovistĀ®
Approved
-
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Further Reading:
  News & More:
Optimized Labelling of Human Monocytes with Iron Oxide MR Contrast Agents
Sunday, 30 November 2003   by rsna2003.rsna.org    
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