Magnetic Resonance - Technology Information Portal Welcome to MRI Technology
Info
  Sheets

Out-
      side
 



 
 'Gadophrin' 
SEARCH FOR    
 
  2 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Result : Searchterm 'Gadophrin' found in 1 term [] and 4 definitions []
1 - 5 (of 5)     
Result Pages : [1]
MRI Resources 
Jobs pool - Contrast Enhanced MRI - Libraries - Patient Information - Case Studies - Spectroscopy pool
 
GadophrinInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Gd-DTPA mesoporphyrin, generic name: gadophrin, central moiety: Gd2+
Gadophrin is a substance under development (Bayer Schering Pharma AG) as a positive enhancing myocardium- and necrosis- targeted MRI contrast agent.

See also Metalloporphyrins and Necrosis Avid Contrast Agent.
spacer
 
• Share the entry 'Gadophrin':  Facebook  Twitter  LinkedIn  
MRI Resources 
Education pool - Safety Training - MRCP - Online Books - NMR - MR Myelography
 
Bayer Schering Pharma AGMRI Resource Directory:
 - Manufacturers -
 
www.bayerscheringpharma.de/scripts/pages/en/index.php The Germany-based pharmaceutical company is the result of the take-over of Schering AG by Bayer AG in 2006. The Bayer Schering Pharma AG is part of the Bayer HealthCare AG, which represents the pharmaceutical part of the Bayer Group. Activities of the Bayer Schering Pharma AG are Diagnostic Imaging, Hematology and Cardiology, Oncology, Primary Care, Specialized Therapeutics and Women's Healthcare. The diagnostic imaging part's contrast agents for MRI, x-ray and computed tomography are 'world-market leaders'.

MRI Contrast Agents:
Contact Information
MAIL
Bayer Schering Pharma AG
51368 Leverkusen
GERMANY
PHONE
+49-30-46-81-2431
FAX
+49-30-46-81-8195
spacer

• View the DATABASE results for 'Bayer Schering Pharma AG' (22).Open this link in a new window


• View the NEWS results for 'Bayer Schering Pharma AG' (25).Open this link in a new window.
 
Further Reading:
  News & More:
Drastic market changes with MRI contrast media and PET radiopharmaceuticals emerging as most promising segments
Thursday, 21 October 2004   by www.news-medical.net    
Epix Pharmaceuticals to shut down
Tuesday, 21 July 2009   by boston.bizjournals.com    
MRI Resources 
Examinations - PACS - Crystallography - Stimulator pool - Sequences - MRI Technician and Technologist Career
 
Gd-DTPA MesoporphyrinInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Short name: Gd-DTPA mesoporphyrin, generic name: gadophrin, central moiety: Gd2+
Gd-DTPA mesoporphyrin is a substance under development (Bayer Schering Pharma AG) as a positive enhancing myocardium- and necrosis- targeted MRI contrast agent.

See also Metalloporphyrins and Necrosis Avid Contrast Agent.
spacer

• View the DATABASE results for 'Gd-DTPA Mesoporphyrin' (2).Open this link in a new window

MRI Resources 
Service and Support - Cochlear Implant - Pregnancy - MRCP - Raman Spectroscopy - Sequences
 
MetalloporphyrinsInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.
 
Porphyrins occur naturally in plants and animals. All porphyrin molecules feature an aromatic macrocycle ring with a central binding site. This site accommodates transition metals, which are held in place by inward-facing nitrogen atoms. Metalloporphyrins have usually a low toxicity and a potential of a selective uptake in tumors or necrosis. These properties are advantageous for a use as MRI tumor specific agents with positive enhancement. These contrast agents enhance tumors on T1 weighted sequences, which are isointense to surrounding tissues. Porphyrin-based compounds have also necrosis avid properties; they can depict the extent of myocardial infarction as defined by histopathology.
Metalloporphyrins are also used in photodynamic therapy of tumors. The compounds contain a 'lone star' metal atom at the center of the ring and are 'bigger than the average porphyrin'. They contain five N atoms in the central chelating core and this allows them to form complexes with large trivalent lanthanide metals, which have useful cancer therapy properties.

See also Classifications, Characteristics, etc., Gadophrin, MnIIITPPS4, Necrosis Avid Contrast Agent.
spacer

• View the DATABASE results for 'Metalloporphyrins' (6).Open this link in a new window

 
Further Reading:
  Basics:
Relaxometric Investigation of Functional Group Placement on MnTPP Derivatives Supports the Role of the Molecular Electrostatic Potential Maps as a Tool to Design New Metalloporphyrins with Larger Relaxivities(.pdf)
   by www.mdpi.org    
Noninvasive Measurements of Infarct Size After Thrombolysis With a Necrosis-Avid MRI Contrast Agent
1999   by circ.ahajournals.org    
MRI Resources 
Jobs - Databases - Stent - Spectroscopy pool - Open Directory Project - Mobile MRI
 
Necrosis Avid Contrast AgentInfoSheet: - Contrast Agents - 
Intro, Overview, 
Characteristics, 
Types of, 
etc.MRI Resource Directory:
 - Contrast Agents -
 
(NACA) Some porphyrin (e.g. Gadophrin-2) and non-porphyrin (e.g. CEIII-60) paramagnetic chelates are able to specifically accumulate in nonviable tissues and can be applied as a MRI contrast agent for acute myocardial infarction and therapeutic necrosis. This function of necrosis avid contrast agents is a unique pathological targetability. These agents can also be exploited for multipurpose applications, because NACAs also bear other common properties including early systemic distribution, albumin binding, hepatocellular uptake and renal elimination.

See also the related poll result: 'The development of contrast agents in MRI is'
spacer

• View the DATABASE results for 'Necrosis Avid Contrast Agent' (9).Open this link in a new window


• View the NEWS results for 'Necrosis Avid Contrast Agent' (1).Open this link in a new window.
 
Further Reading:
  Basics:
Tumor-targeted MR Contrast Agents: Hype or Future Hope?
November 2004   by radiology.rsnajnls.org    
  News & More:
Rockland Technimed: Tissue Viability Imaging
Saturday, 15 December 2007   by www.onemedplace.com    
MRI Resources 
Spine MRI - MRCP - Blood Flow Imaging - Liver Imaging - Education - MRI Physics
 
     1 - 5 (of 5)     
Result Pages : [1]
 Random Page
 
Share This Page
FacebookTwitterLinkedIn

MR-TIP    
Community   
User
Pass
Forgot your UserID/Password ?    



New acceleration techniques will :
reduce scan times 
cause artifacts 
increase expenses 
be useful if you have a lot of experience 
doesn't do much 
never heard of 

Look
      Ups





MR-TIP.com uses cookies! By browsing MR-TIP.com, you agree to our use of cookies.

Magnetic Resonance - Technology Information Portal
Member of SoftWays' Medical Imaging Group - MR-TIP • Radiology-TIP • Medical-Ultrasound-Imaging • 
Copyright © 2003 - 2024 SoftWays. All rights reserved. [ 29 March 2024]
Terms of Use | Privacy Policy | Advertising
 [last update: 2024-02-26 03:41:00]