Low-contrast resolution: The ability to image objects with similar subjects contrast; contrast detectability.
High-contrast resolution: The ability to image small objects having high subject contrast and spatial resolution.

A limitation of abdominal MRI can be the assessment of malignancies by difficulties to distinguish bowel from other organs or malignant masses. The use of oral contrast agents can reduce this problem. Properties of an ideal oral contrast agent are little or no absorption by the stomach or intestines, complete excretion, no motion or susceptibility artifacts, and uniform marking of the GI tract.
Gastrointestinal MRI contrast agents are divided in materials with bright appearance or dark appearance. The choice of a negative or a positive oral contrast agent depends on the specific problem or the pulse sequence.

See also Positive Oral Contrast Agents, Negative Oral Contrast Agents, Gastrointestinal Diamagnetic Contrast Agents, Gastrointestinal Paramagnetic Contrast Agents and Gastrointestinal Superparamagnetic Contrast Agents.

See also the related poll result: 'The development of contrast agents in MRI is'

Contrast enhanced MRI is a commonly used procedure in magnetic resonance imaging. The need to more accurately characterize different types of lesions and to detect all malignant lesions is the main reason for the use of intravenous contrast agents.
Some methods are available to improve the contrast of different tissues. The focus of dynamic contrast enhanced MRI (DCE-MRI) is on contrast kinetics with demands for spatial resolution dependent on the application. DCE-MR imaging is used for diagnosis of cancer (see also liver imaging, abdominal imaging, breast MRI, dynamic scanning) as well as for diagnosis of cardiac infarction (see perfusion imaging, cardiac MRI). Quantitative DCE-MRI requires special data acquisition techniques and analysis software.
Contrast enhanced magnetic resonance angiography (CE-MRA) allows the visualization of vessels and the temporal resolution provides a separation of arteries and veins. These methods share the need for acquisition methods with high temporal and spatial resolution.
Double contrast administration (combined contrast enhanced (CCE) MRI) uses two contrast agents with complementary mechanisms e.g., superparamagnetic iron oxide to darken the background liver and gadolinium to brighten the vessels. A variety of different categories of contrast agents are currently available for clinical use.
Reasons for the use of contrast agents in MRI scans are:
Common Indications:
Brain MRI : Preoperative/pretreatment evaluation and postoperative evaluation of brain tumor therapy, CNS infections, noninfectious inflammatory disease and meningeal disease.
Spine MRI : Infection/inflammatory disease, primary tumors, drop metastases, initial evaluation of syrinx, postoperative evaluation of the lumbar spine: disk vs. scar.
Breast MRI : Detection of breast cancer in case of dense breasts, implants, malignant lymph nodes, or scarring after treatment for breast cancer, diagnosis of a suspicious breast lesion in order to avoid biopsy.

For Ultrasound Imaging (USI) see Contrast Enhanced Ultrasound at Medical-Ultrasound-Imaging.com. See also Blood Pool Agents, Myocardial Late Enhancement, Cardiovascular Imaging, Contrast Enhanced MR Venography, Contrast Resolution, Dynamic Scanning, Lung Imaging, Hepatobiliary Contrast Agents, Contrast Medium and MRI Guided Biopsy.

(CE-FAST) In this technique, the MR signal is sampled immediately prior to each RF pulse. Because the signal is formed by a true spin echo, its contrast is predominantly T2-, rather than T2*-based and is less sensitive to artifacts and signal losses related to field non-uniformity and susceptibility variation. While the signal to noise ratio is limited, the CE-FAST method has the advantage of good contrast.

See Contrast Enhanced Gradient Echo Sequence and Gradient Echo Sequence.

(CE FLASH) A fast T2 weighted imaging sequence utilizing refocused transverse coherence.

See Contrast Enhanced Echo Sequence.